跳转至内容
Merck

L0517

Sigma-Aldrich

白三烯B4

~100 μg/mL in ethanol, ≥97%

别名:

[5S,12R]-二羟基-[6Z,8E,10E,14Z]-二十碳四烯酸

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C20H32O4
CAS号:
分子量:
336.47
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥97%

形狀

liquid

濃度

~100 μg/mL in ethanol

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(O)=O

InChI

1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6-,14-10+,15-11-/t18-,19-/m1/s1

InChI 密鑰

VNYSSYRCGWBHLG-AMOLWHMGSA-N

基因資訊

human ... LTB4R(1241)
rat ... Ltb4r(59264)

正在寻找类似产品? 访问 产品对比指南

生化/生理作用

促炎剂。刺激人单核细胞中c-Fos和c-Jun原癌基因的转录。刺激多形核白细胞的趋化性、聚集和脱粒。

特點和優勢

《受体分类和信号转导》手册的白三烯受体核受体页面重点介绍了该化合物。想要浏览手册的其他页面, 请单击此处

包裝

每种产品附带的数据表包含特殊处理说明。除非另有说明,否则还对甲酯水解的方法进行了描述。

象形圖

FlameExclamation mark

訊號詞

Danger

危險聲明

危險分類

Eye Irrit. 2 - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

57.2 °F - closed cup

閃點(°C)

14.0 °C - closed cup


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

其他客户在看

Ellen Tufvesson et al.
International journal of chronic obstructive pulmonary disease, 12, 3211-3219 (2017-11-16)
The presence of bacteria in the lower airways in COPD results in inflammation, further airway structural damage, and might lead to repeated exacerbations. We have previously shown that chronic colonization of
H E Claesson et al.
International journal of immunopharmacology, 14(3), 441-449 (1992-04-01)
Leukotriene (LT) B4 is a biologically active molecule derived from arachidonic acid via the 5-lipoxygenase pathway. It mediates certain inflammatory and immunological reactions. The role of LTB4 in the immune system has been questioned since lymphocytes have been regarded to
Preeti Subramanian et al.
Investigative ophthalmology & visual science, 57(11), 4581-4588 (2016-09-17)
5-Lipoxygenase (5-LOX) oxygenates arachidonic acid to form 5-hydroperoxyeicosatetraenoic acid, which is further converted into biologically detrimental leukotrienes, such as leukotriene B4 (LTB4). The RPE and retina express the PNPLA2 gene for pigment epithelium-derived factor receptor (PEDF-R), a lipase involved in
Leukotriene A4 hydrolase/aminopeptidase, the gatekeeper of chemotactic leukotriene B4 biosynthesis.
Jesper Z Haeggström
The Journal of biological chemistry, 279(49), 50639-50642 (2004-09-02)
Nicolas Cenac et al.
Gastroenterology, 149(2), 433-444 (2015-04-26)
In mice, activation of the transient receptor potential cation channels (TRP) TRPV1, TRPV4, and TRPA1 causes visceral hypersensitivity. These receptors and their agonists might be involved in development of irritable bowel syndrome (IBS). We investigated whether polyunsaturated fatty acid (PUFA)

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门