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一般說明
与二碘酪氨酸偶联的碘酪氨酸可合成 3，5，3′-三碘甲状腺原氨酸 (T3) 或 3,3′,5′-三碘甲状腺原氨酸 (rT3)。
應用
3-碘-L-酪氨酸已作为酪氨酸羟化酶的抑制剂用于 果蝇 和蚕蛹。
生化／生理作用
3-碘酪氨酸 (3-IY) 抑制酪氨酸羟化酶，后者催化酪氨酸形成左旋多巴。严重甲减和甲状腺肿时，碘酪氨酸脱碘酶缺乏导致血清和尿中 3-IY 水平升高。
TH（酪氨酸 3-羟化酶）负责催化去甲肾上腺素能生物合成途径的第一步。TH 突变 与酪氨酸羟化酶缺乏相关，导致诸如婴儿型帕金森综合征和多巴（ 多巴胺 ）反应性肌张力障碍以及围产期发病的脑病。
酪氨酸羟化酶抑制剂。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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L G Harsing et al.
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