推荐产品
product name
白介素-1β 来源于大鼠, IL-1β, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
生物源
rat
品質等級
重組細胞
expressed in E. coli
化驗
≥98% (SDS-PAGE and HPLC)
形狀
lyophilized powder
效力
0.01-0.1 ng/mL ED50/EC50
分子量
17.3 kDa
包裝
pkg of 10 and 50 μg
技術
cell culture | mammalian: suitable
雜質
<0.1 EU/μg
UniProt登錄號
儲存溫度
−20°C
基因資訊
rat ... Il1b(24494)
一般說明
白细胞介素-1(IL-1),最初称为淋巴细胞活化因子(LAF),可激活T细胞和淋巴细胞,从而使其进一步增殖并分泌白细胞介素-2。1 IL-1主要从受刺激的巨噬细胞和单核细胞中释放出来,但也可从其他几种细胞中释放出来,2 并被认为在炎症和免疫反应中起关键作用。3 IL-1的其他同义词包括:内源性热原(EP)、促有丝分裂蛋白(MP)、Helper Peak-1(HP-1)、T细胞替代因子III(TRF III或TRFH)、B细胞活化因子(BAF)、以及B细胞分化因子(BDF)。4 两种密切相关的试剂,白细胞介素-1α (IL-1α )和白细胞介素-1β(IL-1β)可结合相同的细胞表面受体,并引起几乎相同的生物反应,但它们的氨基酸序列中仅具有25%的同源性。重组大鼠IL-1β是一种含有153个氨基酸残基的,大小为17.3kDa的蛋白质。
外觀
从0.2 μm过滤的缓冲溶液中冻干。
分析報告
使用鼠D10S细胞在细胞增殖测定中对生物活性进行检测。
引用
1. Gery, I., et al., J. Exp. Med., 136, 128 (1972).
2. Oppenheim, J. J., et al., Immunol. Today, 7, 45 (1986).
3. Durum, S. K., et al., Annu. Rev. Immunol., 3, 263 (1985).
4. Aarden, L., et al., J. Immunol., 123, 2928 (1979).
5. Symons, J., et al., Lymphokines and Interferons, A Practical Approach, Clemens, M., et al., (eds.), IRL Press, Oxford (1987).
2. Oppenheim, J. J., et al., Immunol. Today, 7, 45 (1986).
3. Durum, S. K., et al., Annu. Rev. Immunol., 3, 263 (1985).
4. Aarden, L., et al., J. Immunol., 123, 2928 (1979).
5. Symons, J., et al., Lymphokines and Interferons, A Practical Approach, Clemens, M., et al., (eds.), IRL Press, Oxford (1987).
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Journal of neurophysiology, 117(6), 2282-2291 (2017-03-17)
Excessive inflammation including IL-1β-initiated signaling is among the earlies reactions that can cause neuronal damage following spinal cord injury (SCI). It has been suggested that microRNAs may participate in stem cell repair to facilitate functional recovery following SCI. In this
商品
The Interleukins comprise a disparate group of cytokines and growth factors that are produced by and released from leukocytes. Interleukin-1β (1L-1β) is released primarily from stimulated macrophages and monocytes and plays a key role in inflammatory and immune responses and may induce anti-tumor immunity.
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门