推荐产品
生物源
human
品質等級
重組細胞
expressed in NSO cells
化驗
>97% (SDS-PAGE)
形狀
lyophilized powder
分子量
36 kDa
包裝
pkg of 0.1 mg
雜質
endotoxin, tested
UniProt登錄號
儲存溫度
−20°C
基因資訊
human ... IL1R1(3554)
一般說明
Interleukin-1 type 1 receptor (IL1R1) is a glycoprotein. It is mainly expressed on endothelial cells, epithelial cells, hepatocytes, fibroblasts, epidermal dendritic cells as well as T lymphocytes.
生化/生理作用
Interleukin-1 (IL-1), a cytokine, is a key regulator of acute and chronic inflammation. The IL-1 associated responses are achieved by association of IL-1 with IL-1 type 1 receptor (IL1R1).
Recombinant human IL-1 soluble receptor I is a transmembrane protein and a member of the immunoglobulin superfamily. It is expressed predominantly by T cells, fibroblasts, and endothelial cells.
外觀
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5.0 mg bovine serum albumin
分析報告
The bioactivity is measured by its ability to inhibit the IL-1β-dependent proliferation of a murine helper T cell line, D10.G4.1.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Cellular & molecular immunology, 12(2), 222-230 (2014-07-01)
The biological activity of the multifunctional cytokine interleukin-1 (IL-1) is mediated by its receptors. The aim of this study was to determine if an association exists between single nucleotide polymorphisms (SNPs) in the IL-1 type 1 and 2 receptor genes
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