I3525

Interleukin-17A human

≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• 别名: CTLA-8, IL-17
• MDL號碼: MFCD01094096
• 分類程式碼代碼: 12352202
• NACRES: NA.32

属性

• 生物源: human
• 品質等級: 100
• 重組細胞: expressed in E. coli
• 化驗: ≥98% (SDS-PAGE)
• 形狀: lyophilized powder
• 效力: ≤2.0 ng/mL ED₅₀
• 分子量: 31 kDa
• 包裝: pkg of 50 μg
• 技術: cell culture | mammalian: suitable
• 雜質: endotoxin, tested (endotoxin level is less than 0.1 ng per μg cytokine (1 EU/μg).)
• UniProt登錄號: Q16552
• 儲存溫度: −20°C
• 基因資訊: human ... IL17A(3605)

说明

生化／生理作用

IL-17, initially known as CTLA-8, is a T cell-expressed polypeptide that appears to be involved in the regulation of the hematopoietic system. IL-17 has been shown to induce IL-6, IL-8, and G-CSF production by fibroblasts; all of these cytokines have demonstrated effects on hematopoiesis.

外觀

Lyophilized with no additives.

分析報告

• The biological activity of human IL-17 is measured by its ability to induce IL-6 production using NHDF cells.
• Biological activity is also determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblast. The expected ED50 is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)