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Merck

H7166

Sigma-Aldrich

IL-3 human

HumanKine®, recombinant, Xeno-free, >95% (SDS-PAGE), suitable for cell culture

别名:

IL-3

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About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.77

product name

白细胞介素-3 人, IL-3, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture

生物源

human

品質等級

重組細胞

expressed in HEK 293 cells

化驗

>95% (SDS-PAGE)

形狀

lyophilized powder

效力

≤2 ng/mL EC50

品質

endotoxin tested

分子量

dimer 17-45 kDa (glycosylated)

包裝

pkg of 10 μg

製造商/商標名

HumanZyme

技術

cell culture | mammalian: suitable

雜質

<1 EU/μg

UniProt登錄號

儲存溫度

−20°C

基因資訊

human ... IL3(3562)

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生化/生理作用

白介素3(IL-3)是一种多功能蛋白,起初被称为克隆形成单位刺激活性(CFU-SA),由活化的T淋巴细胞产生。IL-3在多能造血祖细胞的早期发育中可支持多谱系克隆的形成。IL-3已显示出可从琼脂悬浮的骨髓细胞诱导巨噬细胞、嗜中性粒细胞、肥大细胞和巨核细胞的克隆形成。IL-3也可与IL-2发生互作,以刺激T淋巴细胞的生长并诱导活化B细胞分泌IgG。IL-3的其他同义词包括泛特异性造血素、多克隆刺激因子、肥大细胞生长因子、爆发促进活性、组胺生成细胞刺激因子、P细胞刺激因子和WEHI-3因子。

外觀

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

準備報告

HumanKine Interleukin-3 (IL-3), expressed in human HEK 293 cells, is a glycosylated monomer with an apparent molecular mass of 17-45 kDa due to glycosylation, which is absent when this cytokine is expressed in E. coli. Production in human HEK 293 cells offers authentic glycosylation which contributes to stability in cell growth media and other applications.

分析報告

The activity was determined by the dosedependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).

法律資訊

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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