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product name
8-羟基-2′-脱氧鸟苷, ≥98% (TLC)
品質等級
化驗
≥98% (TLC)
儲存溫度
2-8°C
SMILES 字串
O=C1C(NC(N2C3CC(O)C(CO)O3)=O)=C2NC(N)=N1
InChI
1S/C10H13N5O5/c11-9-13-7-6(8(18)14-9)12-10(19)15(7)5-1-3(17)4(2-16)20-5/h3-5,16-17H,1-2H2,(H,12,19)(H3,11,13,14,18)
InChI 密鑰
HCAJQHYUCKICQH-UHFFFAOYSA-N
應用
8-羟基-2′-脱氧鸟苷已用于以下情形:
- 作为标准品,通过电化学检测分析正常和异常妊娠胎盘中的氧化DNA损伤
- 借助电化学检测(ECD),作为标准品用于高效液相色谱法(HPLC)
- 作为HPLC标准品和氧化应激尿液标志物,评估绿咖啡豆提取物的潜在抗氧化活性(GCBE) 体内
- 作为标准品用于LC/MS/MS分析
生化/生理作用
8-羟基-2′-脱氧鸟苷的水平有助于评估喉癌个体的氧化应激和DNA损伤。因此它可以用作活性氧(ROS)诱导DNA损伤的主要生物标志物。
标记化合物通常指示与诱变和致癌作用相关的DNA损伤
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
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