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Merck

G7387

Sigma-Aldrich

Gly-His-Lys 乙酸盐

BioXtra, γ-irradiated, suitable for cell culture

别名:

肝细胞生长因子

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About This Item

线性分子式:
C14H24N6O4C2H4O2
CAS号:
分子量:
400.43
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.77

生物源

synthetic (organic)

品質等級

無菌

γ-irradiated

產品線

BioXtra

形狀

powder

分子量

400.43 g/mol

包裝

pkg of 5 mg

技術

cell culture | mammalian: suitable

雜質

<2 EU/mL

顏色

white

溶解度

H2O: soluble 0.5 mg/mL, clear, colorless

儲存溫度

−20°C

SMILES 字串

CC(O)=O.NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(O)=O

InChI

1S/C14H24N6O4.C2H4O2/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;1-2(3)4/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24);1H3,(H,3,4)/t10-,11-;/m0./s1

InChI 密鑰

MGNUTAFMLGJBGV-ACMTZBLWSA-N

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Amino Acid Sequence

Gly-His-Lys

應用

甘氨酰-组氨酰-赖氨酰(Gly-His-Lys)乙酸盐已用于:
  • 用作培养人甲状腺细胞的含血清培养基的成分
  • 用作培养Fisher大鼠甲状腺细胞的补充剂
  • 用作杜氏改良杜氏改良Eagle培养基 (DMEM)/HamF12/间充质干细胞培养基成分,培养间充质干细胞

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

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Ana Trapaidze et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 17(1), 37-47 (2011-09-08)
The peptides Asp-Ala-His-Lys (DAHK) and Gly-His-Lys (GHK) are naturally occurring Cu(II)-chelating motifs in human serum and cerebrospinal fluid. Here, the sensitive thermodynamic technique isothermal titration calorimetry was used to study the energetics of Cu(II) binding to DAHK and GHK peptides
M Kawase et al.
Biological & pharmaceutical bulletin, 22(9), 999-1001 (1999-10-08)
A tripeptide growth factor, glycyl-L-histidyl-L-lysine (GHK), was immobilized on the surface of poly(vinylalcohol)-quarternized stilbazole (PVA-SbQ) gel. The photoreactive substance, 4-(3-trifluoromethylazirino)benzoyl-N-hydroxysuccinimide (TDBA-OSu), was employed to link the gel and ligand GHK. The density of immobilized GHK was 70 nmol/cm2. Isolated rat
Y Zheng et al.
Organic letters, 3(21), 3277-3280 (2001-10-12)
[structure: see text]. A new fluorescent chemosensor for Cu2+ ions was synthesized by modifying the tripeptide glycyl-histidyl-lysine (GHK) with 9-carbonylanthracene via the standard Fmoc solid-phase peptide synthesis method. While significant fluorescence quenching was observed from the molecule upon binding with
A Siméon et al.
Life sciences, 67(18), 2257-2265 (2000-10-25)
Glycyl-histidyl-lysine-Cu2+ (GHK-Cu) is a tripeptide-copper complex known to be a potent wound healing agent. We previously showed its ability to stimulate in vitro and in vivo the synthesis of extracellular matrix components. The aim of this study was to determine
Giangiacomo Beretta et al.
Journal of pharmaceutical and biomedical analysis, 47(3), 596-602 (2008-04-02)
Acrolein (ACR) is a well-known carbonyl toxin produced by lipid peroxidation of polyunsaturated fatty acids, which is involved in several life-threatening pathologies such as Alzheimer disease, arteriosclerosis, diabetes, and nephropathy. The aim of this work was to study the quenching

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