推荐产品
品質等級
化驗
≥98% (HPLC)
形狀
powder
溶解度
1 M NH4OH: 20 mg/mL, clear, colorless to faintly yellow
儲存溫度
−20°C
SMILES 字串
OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(Cl)C(=O)NC2=O
InChI
1S/C9H11ClN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
InChI 密鑰
NJCXGFKPQSFZIB-RRKCRQDMSA-N
正在寻找类似产品? 访问 产品对比指南
應用
5-氯-2′-脱氧尿苷已用于：
- 利用动物模型，通过免疫组化分析和双S期标记研究细胞周期动力学
- 使用动物模型分析细胞周期长度
- 标记HEK293T细胞进行分子梳理试验
生化／生理作用
用5-氯-2′-脱氧尿苷(CldU)标记的DNA是分析和量化DNA复制、修复和重组的有效工具。CldU是一种有效的诱变剂、分裂剂和毒物。它被用作胸腺嘧啶类似物，并被发现改变dNTP池，可能导致细胞周期停滞。CldU产生姐妹染色单体交换，但与其他胸腺嘧啶类似物相比，对电离辐射的响应较小。5-氯-2′-脱氧尿苷（CldU，氯脱氧尿苷）用于研究DNA和DNA前体的次氯酸损伤引起碱基错配的潜在可能。在识别DNA复制位点的实验方案中，5-氯-2′-脱氧尿苷(CldU)可掺入DNA以便通过CldU抗体进行后续的免疫荧光成像。氯脱氧尿苷可与其他卤化尿苷，如碘脱氧尿苷(IdU)，共同作为标记底物使用。
訊號詞
Warning
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
S M Ohline et al.
Brain structure & function, 223(7), 3213-3228 (2018-05-26)
Early during their maturation, adult-born dentate granule cells (aDGCs) are particularly excitable, but eventually develop the electrophysiologically quiet properties of mature cells. However, the stability versus plasticity of this quiet state across time and experience remains unresolved. By birthdating two
Masaya Kimoto et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 56(1), 15-24 (2007-09-19)
To identify stem cells in salivary glands, label-retaining cells (LRCs) were established in rat submandibular glands. Developing and regenerating glands were labeled with bromodeoxyuridine (BrdU). To cause gland regeneration, the glands were injured by duct obstruction. BrdU LRCs were observed
Beatrice Rondinelli et al.
Nature cell biology, 19(11), 1371-1378 (2017-10-17)
The emergence of resistance to poly-ADP-ribose polymerase inhibitors (PARPi) poses a threat to the treatment of BRCA1 and BRCA2 (BRCA1/2)-deficient tumours. Stabilization of stalled DNA replication forks is a recently identified PARPi-resistance mechanism that promotes genomic stability in BRCA1/2-deficient cancers.
Fan Xuan et al.
Cell death & disease, 9(11), 1062-1062 (2018-10-20)
MYC-induced nuclear antigen (MINA53) is a JmjC (jumonji C domain)-containing protein, which is highly expressed in many cancers including glioblastoma. We have revealed in our previous report that MINA53 is a poor prognostic indicator for glioblastoma patients, and knockdown of
Eyal Ben-David et al.
Cancer research, 74(19), 5532-5540 (2014-08-16)
Colorectal cancer develops in a sequential, evolutionary process, leading to a heterogenic tumor. Comprehensive molecular studies of colorectal cancer have been previously performed; still, the process of carcinogenesis is not fully understood. We utilized gene expression patterns from 94 samples
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门