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C6305

Sigma-Aldrich

氯氮平标准液

≥98% (TLC), powder, D₄-dopamine receptor antagonist

别名:

8-氯-11-（4-甲基-1-哌嗪基）-5H-二苯并[b,e][1,4]二氮杂卓

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About This Item

经验公式（希尔记法）:
C18H19ClN4
CAS号:
5786-21-0
分子量:
326.82
MDL號碼:
MFCD00153785
分類程式碼代碼:
12352200
PubChem物質ID:
24277892
NACRES:
NA.77

product name

氯氮平标准液,

形狀

powder

品質等級

300

溶解度

ethanol: 1 mg/mL
0.1 M HCl: 30 mg/mL
DMSO: 4.8 mg/mL

起源

Novartis

SMILES 字串

CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24

InChI

1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3

InChI 密鑰

QZUDBNBUXVUHMW-UHFFFAOYSA-N

基因資訊

human ... ADRA1A(148) , ADRA2A(150) , ADRA2C(152) , CHRM1(1128) , DRD2(1813) , DRD3(1814) , DRD4(1815) , HRH1(3269) , HRH4(59340) , HTR2A(3356) , HTR2C(3358) , HTR3A(3359) , HTR3B(9177) , HTR3C(170572) , HTR3D(200909) , HTR3E(285242) , HTR6(3362) , HTR7(3363) , KCNH1(3756) , KCNH2(3757) , UGT1A4(54657)
rat ... Adra1a(29412) , Adra2a(25083) , Adrb1(24925) , Chrm1(25229) , Drd1a(24316) , Drd2(24318) , Drd3(29238) , Drd4(25432) , Hrh1(24448) , Htr1a(24473) , Htr1b(25075) , Htr2a(29595) , Htr2b(29581) , Htr2c(25187) , Htr3a(79246) , Htr7(65032) , Slc6a4(25553)

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生化／生理作用

非典型抗精神病化合物。D 4 -多巴胺受体的选择性拮抗剂。5-HT2A、5-HT2C、5-HT3、 5-HT6和 5-HT7 5-羟色胺受体拮抗剂。

特點和優勢

《受体分类和信号转导》手册的 组胺受体 页面有该化合物的介绍。想要浏览手册的其他页面， 请单击此处。
该化合物由Novartis开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。

同類產品

产品编号
说明
价格

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險聲明

H301

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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P B Bergqvist et al.
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Habituation is a simple form of learning where animals learn to reduce their responses to repeated innocuous stimuli [1]. Habituation is thought to occur via at least two temporally and molecularly distinct mechanisms, which lead to short-term memories that last
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