所有图片(1)
About This Item
经验公式（希尔记法）:
C13H17ClN2O2
CAS号:
分子量:
268.74
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推荐产品
化驗
≥98% (HPLC)
形狀
solid
顏色
white
溶解度
DMSO: >20 mg/mL
起源
Roche
儲存溫度
room temp
SMILES 字串
Clc1ccc(cc1)C(=O)NCCN2CCOCC2
InChI
1S/C13H17ClN2O2/c14-12-3-1-11(2-4-12)13(17)15-5-6-16-7-9-18-10-8-16/h1-4H,5-10H2,(H,15,17)
InChI 密鑰
YHXISWVBGDMDLQ-UHFFFAOYSA-N
生化／生理作用
吗氯贝胺可作为细胞色素P450 2C19（CYP2C19）的底物。它也可充当细胞色素P450 2D6（CYP2D6）、细胞色素P450 1A2（CYP1A2和CYP2C19）的抑制剂。吗氯贝胺还和B细胞淋巴瘤2（BcL-2）表达的增加有关。它还通过胞外调节激酶（ERK）途径使神经干细胞（NSC）分化为血清素能神经元（serotoninergic neuron）。
吗氯贝胺是一种可逆性单胺氧化酶A抑制剂（MAOI）； 抗抑郁药。人体内的消除半衰期= 1 -3小时；绝对口服生物利用度。与其他MAO抑制剂不同，它与酪胺合用不会显著增加人的血压。
特點和優勢
该化合物收录于受体分类和信号转导手册的《多巴胺和去甲肾上腺素代谢》页面。想要浏览手册的其他页面， 请单击此处。
訊號詞
Danger
危險分類
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
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Sleep apnoea is a common disorder presenting with somatic comorbidities and psychiatric symptoms. This case report describes a 43-year-old man with an organic depressive disorder due to obstructive sleep apnoea. Initially, an atypical depressive episode or schizophrenic residual syndrome had
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