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Merck

C0742

Sigma-Aldrich

CKI-7 二盐酸盐

≥98% (HPLC), solid, CK1 inhibitor

别名:

N-(2-氨基乙基)-5-氯异喹啉-8-磺酰胺 二盐酸盐

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About This Item

经验公式(希尔记法):
C11H12ClN3O2S · 2HCl
分子量:
358.67
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

产品名称

CKI-7 二盐酸盐, ≥98% (HPLC), solid

品質等級

化驗

≥98% (HPLC)

形狀

solid

儲存條件

desiccated

顏色

white to light tan

溶解度

H2O: >5 mg/mL

儲存溫度

−20°C

SMILES 字串

Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12

InChI

1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H

InChI 密鑰

JUAVTXYOCISSSL-UHFFFAOYSA-N

生化/生理作用

CKI-7是一种CK1抑制剂;也能抑制SGK、S6K1和MSK1。 CKI-7与CK1一样能有效抑制SGK。IC50 = 6 μM。

注意

材料是吸湿性的

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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