推荐产品
产品名称
L -2-氨基己二酸, ≥98% (TLC)
品質等級
化驗
≥98% (TLC)
形狀
powder
mp
203-205 °C (dec.) (lit.)
SMILES 字串
N[C@@H](CCCC(O)=O)C(O)=O
InChI
1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/t4-/m0/s1
InChI 密鑰
OYIFNHCXNCRBQI-BYPYZUCNSA-N
基因資訊
human ... GLUL(2752) , LGSN(51557)
rat ... Grm1(24414) , Grm2(24415) , Grm4(24417) , Grm5(24418) , Grm6(24419)
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一般說明
L-2-氨基己二酸/α-氨基己二酸酯是一种葡聚糖毒素，其是谷氨酰胺的结构类似物。它由赖氨酸蔗糖（SAC）/哌酸（PIP）途径的分解代谢产生。
應用
L-2-氨基己二酸已被用作大鼠星形胶质细胞特异的一种胶质毒素。它也已作为发酵食品样品氨基酸分析中的内标。
生化／生理作用
L-2-氨基己二酸可抑制谷氨酰胺合成酶和 γ-谷氨酰半胱氨酸合成酶。它可调节葡萄糖代谢，并在糖尿病患者中水平更高。L-2-氨基己二酸在抑制C2C12肌管中的自噬中起关键作用。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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