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Merck

75447

Sigma-Aldrich

2-氧代己二酸 单钠盐

≥95.0% (HPLC)

别名:

α-酮己二酸 单钠盐, 2-己二酸, 2-氧己二酸 单钠盐

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About This Item

经验公式(希尔记法):
C6H8O5
CAS号:
分子量:
160.12
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.25

化驗

≥95.0% (HPLC)
≥97.0% (T)

形狀

powder

脂質類型

saturated FAs

儲存溫度

2-8°C

SMILES 字串

OC(=O)CCCC(=O)C(O)=O

InChI

1S/C6H8O5/c7-4(6(10)11)2-1-3-5(8)9/h1-3H2,(H,8,9)(H,10,11)

InChI 密鑰

FGSBNBBHOZHUBO-UHFFFAOYSA-N

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應用


  • Engineering of phenylalanine dehydrogenase from Thermoactinomyces intermedius for the production of a novel homoglutamate: Showcases the application of 2-oxoadipic acid in enzyme engineering, enhancing biocatalytic processes for the production of novel compounds, vital for pharmaceutical and chemical industries (Tariq et al., 2022).

生化/生理作用

TCA循环和赖氨酸生物合成之间的重要代谢物。 对于线粒体代谢物转运蛋白具有意义。

包裝

无底玻璃瓶。内含物在插入的融合锥体内。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Natalia S Nemeria et al.
Biochimica et biophysica acta. Bioenergetics, 1859(9), 932-939 (2018-05-13)
Herein are reported findings in vitro suggesting both functional and regulatory cross-talk between the human 2-oxoglutarate dehydrogenase complex (hOGDHc), a key regulatory enzyme within the tricarboxylic acid cycle (TCA cycle), and a novel 2-oxoadipate dehydrogenase complex (hOADHc) from the final
D G Hine et al.
Biomedical mass spectrometry, 11(7), 332-339 (1984-07-01)
Numerous abnormal metabolites were identified in large amounts in the urine of hypoglycin-treated rats using capillary gas chromatography/mass spectrometry-computer analysis. These metabolites are not detectable in significant amounts in normal rats' urine. Ten of them have not been previously associated
A fatal case of 2-keto-, 2-hydroxy- and 2-aminoadipic aciduria: relation of organic aciduria to phenotype?
C Jakobs et al.
Journal of inherited metabolic disease, 15(2), 279-280 (1992-01-01)
Nikolaus Sonnenschein et al.
BMC systems biology, 6, 41-41 (2012-05-16)
Integrating gene expression profiles and metabolic pathways under different experimental conditions is essential for understanding the coherence of these two layers of cellular organization. The network character of metabolic systems can be instrumental in developing concepts of agreement between expression
D Darmaun et al.
Journal of chromatography, 620(1), 33-38 (1993-10-22)
A method is described for measuring glutamine (GLN) and alpha-ketoglutarate (KG) concentration and specific activity (SA) using high-performance liquid chromatography (HPLC). Plasma GLN and KG are separated on miniature ion-exchange columns. KG is derivatized with O-phenylene diamine, the derivative is

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