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Merck
所有图片(1)

主要文件

A7075

Sigma-Aldrich

Adrenocorticotropic Hormone rat

≥95% (HPLC)

别名:

Adrenocorticotropic hormone fragment 1-39, Corticotropin A

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About This Item

经验公式(希尔记法):
C210H315N57O57S
CAS号:
分子量:
4582.16
MDL號碼:
分類程式碼代碼:
51111800
NACRES:
NA.32
生物源:
rat
形狀:
powder
化驗:
≥95% (HPLC)

生物源

rat

品質等級

無菌

non-sterile

化驗

≥95% (HPLC)

形狀

powder

溶解度

1% acetic acid: 1.00-1.04 mg/mL, clear, colorless
water: 1.00-1.04 mg/mL, clear, colorless

UniProt登錄號

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

rat ... Pomc(24664)

Amino Acid Sequence

Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Val-Ala-Glu-Asn-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe

生化/生理作用

Stimulates synthesis and secretion of glucocorticoids by adrenal cortex.

其他說明

Lyophilized from 0.1% TFA in H2O

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hasan Arrat et al.
PloS one, 10(5), e0125638-e0125638 (2015-05-09)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a complex etiology and pathology that makes the development of new therapies difficult. ACTH has neurotrophic and myotrophic effects, but has not been tested in an ALS mouse model. The G93A-SOD1
Carla Schulz et al.
American journal of physiology. Endocrinology and metabolism, 298(2), E237-E244 (2009-11-19)
ACTH and alpha-melanocyte-stimulating hormone (alpha-MSH) are both consecutively processed from proopiomelanocortin (POMC), which is synthesized in hypothalamic arcuate neurons innervating the paraventricular nuclei (PVN). POMC secretion/synthesis is regulated by energy availability. ACTH and alpha-MSH bind with equal affinity to melanocortin-4

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