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A3085

Sigma-Aldrich

5-(N-乙基-N-异丙基)阿米洛利

别名:

EIPA

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About This Item

经验公式（希尔记法）:
C11H18ClN7O
CAS号:
1154-25-2
分子量:
299.76
MDL號碼:
MFCD00151710
分類程式碼代碼:
12352200
PubChem物質ID:
24278223
NACRES:
NA.77

生物源

synthetic

品質等級

200

化驗

≥98% (TLC)

形狀

powder

mp

202-205 °C (lit.)

溶解度

methanol: 9.80-10.20 mg/mL, clear, light yellow to yellow

儲存溫度

2-8°C

SMILES 字串

CCN(C(C)C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N

InChI

1S/C11H18ClN7O/c1-4-19(5(2)3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20)

InChI 密鑰

QDERNBXNXJCIQK-UHFFFAOYSA-N

基因資訊

human ... SCNN1A(6337) , SCNN1B(6338) , SCNN1D(6339) , SCNN1G(6340) , SLC9A1(6548) , SLC9A5(6553)
mouse ... Scnn1a(20276) , Scnn1b(20277) , Scnn1d(140501) , Scnn1g(20278)
rat ... Scnn1a(25122) , Scnn1b(24767) , Scnn1g(24768) , Slc9a1(24782) , Slc9a2(24783) , Slc9a3(24784) , Slc9a4(24785)

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應用

5-(N-乙基-N-异丙基)阿米洛利已用于：
  • 作为内皮细胞生长培养基补充剂，培养人肺微血管内皮细胞
  • 加入Pluronic F-127贮备液，用于果蝇幼虫活体成像
  • 加入氯化胆碱溶液，作为灌注液用于研究Na+/H+对体内空肠环路灌注的抑制作用

生化／生理作用

Na+/H+反向转运的选择性阻断剂

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315 - H319 - H335

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

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