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Merck

A2559

Sigma-Aldrich

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide

≥97% (HPLC), powder

别名:

Ac-DEVD-pNA

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About This Item

经验公式(希尔记法):
C26H34N6O13
分子量:
638.58
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.32

品質等級

化驗

≥97% (HPLC)

形狀

powder

顏色

white

儲存溫度

−20°C

SMILES 字串

CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI

1S/C26H34N6O13/c1-12(2)22(26(43)30-18(11-21(38)39)24(41)28-14-4-6-15(7-5-14)32(44)45)31-23(40)16(8-9-19(34)35)29-25(42)17(10-20(36)37)27-13(3)33/h4-7,12,16-18,22H,8-11H2,1-3H3,(H,27,33)(H,28,41)(H,29,42)(H,30,43)(H,31,40)(H,34,35)(H,36,37)(H,38,39)/t16-,17-,18-,22-/m0/s1

InChI 密鑰

GGXRLUDNGFFUKI-ORGXJRBJSA-N

基因資訊

human ... CASP3(836)

Amino Acid Sequence

NAc-Asp-Glu-Val-Asp-pNA

應用

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide has been used as a chromogenic substrates for determining caspase-3 and caspase-8 activities in liver tissue homogenates and caspase 3 activity in aortic vascular smooth muscle cells and neuroblastoma cell lines.

生化/生理作用

Colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.

相關產品

产品编号
说明
价格

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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