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A1640

Sigma-Aldrich

腺苷5′-O-硫代单磷酸 二锂盐

≥98%

别名:

5′-AMPS

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About This Item

经验公式（希尔记法）:
C10H12Li2N5O6PS
CAS号:
93839-85-1
分子量:
375.15
MDL號碼:
MFCD00042996
分類程式碼代碼:
41106305
PubChem物質ID:
24890572
NACRES:
NA.51

品質等級

200

化驗

≥98%

形狀

powder

儲存溫度

−20°C

SMILES 字串

[Li+].[Li]SP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23

InChI

1S/C10H14N5O6PS.2Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(21-10)1-20-22(18,19)23;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,23);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

InChI 密鑰

FZXPFDFAEUBVHA-IDIVVRGQSA-L

相关类别

應用

腺苷-5′′-O-硫代单磷酸酯(5'-AMPS)是一种5′-O-硫代磷酸酯，可与腺苷5′-O-(2-硫代二磷酸酯)和腺苷5′-O-(3-硫代三磷酸酯)一起作为磷酸水解酶的抑制剂。AMPS是平滑肌内皮胞外-5′-核苷酸酶的底物。5′APMS是大鼠多形核(PMN)白细胞中5-脂氧合酶活性的刺激物。组氨酸三联体核苷酸结合蛋白1（HINT-1）磷酰胺酶可将核苷-5′-O-硫代磷酸酯（如5′-AMPS）转化为核苷5′-O-磷酸酯。

象形圖

Health hazardExclamation mark
GHS08,GHS07

訊號詞

Warning

危險聲明

H302,H371

危險分類

Acute Tox. 4 Oral - STOT SE 2

標靶器官

Eyes,Central nervous system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
SLCC1047
SLBV0921
SLBP6301V
100M1621
029K1237

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The Biochemical journal, 230(2), 503-507 (1985-09-01)
We compared the properties of the ectonucleotidases (nucleoside triphosphatase, EC 3.6.1.15; nucleoside diphosphatase, EC 3.6.1.6; 5'-nucleotidase, EC 3.1.3.5) in intact pig aortic smooth-muscle cells in culture with the properties that we previously investigated for ectonucleotidases of aortic endothelial cells [Cusack
D Denis et al.
Archives of biochemistry and biophysics, 273(2), 592-596 (1989-09-01)
The stable nucleotide analog guanosine 5'-O-(3-thiotriphosphate) (GTP gamma S) was found to be a very potent activator of 5-lipoxygenase in cell-free preparations from rat polymorphonuclear (PMN) leukocytes, causing a 10-fold stimulation of arachidonic acid oxidation at concentrations as low as
Magdalena Ozga et al.
The Journal of biological chemistry, 285(52), 40809-40818 (2010-10-14)
Nucleoside 5'-O-phosphorothioates are formed in vivo as primary products of hydrolysis of oligo(nucleoside phosphorothioate)s (PS-oligos) that are applied as antisense therapeutic molecules. The biodistribution of PS-oligos and their pharmacokinetics have been widely reported, but little is known about their subsequent
D J Montague et al.
European journal of biochemistry, 139(3), 529-534 (1984-03-15)
Adenosine diphosphatase (ADPase) activity and ATPase activity were assayed in rat liver mitochondria and outer mitochondrial membrane preparations with [beta-32P]ADP and [gamma-32P]ATP as substrates. Inhibition studies were performed with the mitochondrial ATPase inhibitor oligomycin and the adenine nucleotide transport inhibitor
Adenosine 5'-phosphorothioate. A nucleotide analog that is a substrate, competitive inhibitor, or regulator of some enzymes that interact with adenosine 5'-phosphate.
A W Murray et al.
Biochemistry, 7(11), 4023-4029 (1968-11-01)

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