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Merck

73677

Sigma-Aldrich

4-硝基苯基 β-D-葡糖苷酸

β-glucuronidase substrate, chromogenic, ≥99.0% (TLC), powder or crystals, suitable as substrate for β-glucuronidase test

别名:

4-硝基苯基-β-D-吡喃葡萄糖醛酸, PNPG

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About This Item

经验公式(希尔记法):
C12H13NO9
CAS号:
分子量:
315.23
Beilstein:
1438576
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32

product name

4-硝基苯基 β-D-葡糖苷酸, ≥99.0% (TLC)

品質等級

化驗

≥99.0% (TLC)

形狀

powder or crystals

光學活性

[α]20/D −102±3°, c = 1% in ethanol

雜質

≤0.05% free 4-nitrophenol
≤7% water

溶解度

H2O: 0.1 g/mL, clear, faintly yellow

適合性

suitable as substrate for β-glucuronidase test

儲存溫度

−20°C

SMILES 字串

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)[N+]([O-])=O

InChI

1S/C12H13NO9/c14-7-8(15)10(11(17)18)22-12(9(7)16)21-6-3-1-5(2-4-6)13(19)20/h1-4,7-10,12,14-16H,(H,17,18)/t7-,8-,9+,10-,12+/m0/s1

InChI 密鑰

QSUILVWOWLUOEU-GOVZDWNOSA-N

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應用

4-硝基苯基β-D-葡萄糖醛酸苷用于测定尿液样本中β-葡萄糖醛酸苷酶的活性,盲肠内容物消化物细菌和牛肝中β-葡萄糖醛酸苷酶的活性。 也用来研究苦味叶下珠提取物对β-葡萄糖醛酸苷酶的抑制作用。

基底

用于 β-葡萄糖醛酸酶(GUS)基因检测的显色底物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Effect of tobacco smoking on albumin concentration and beta-glucuronidase activity in urine of smelters
Bizonn A, et al.
Przegla?d Lekarski, 71(11), 581-584 (2014)
Synthesis of Glycaro-1, 5-lactams and Tetrahydrotetrazolopyridine-5-carboxylates: Inhibitors of beta-D-Glucuronidase and alpha-L-Iduronidase
Pabba J, et al.
Helvetica Chimica Acta, 89(4), 635-666 (2006)
Effect of dietary honey on intestinal microflora and toxicity of mycotoxins in mice
El-Arab AME, et al.
BMC Complementary and Alternative Medicine, 6(1), 6-6 (2006)
H Iwabuchi et al.
Journal of chromatography, 414(1), 139-148 (1987-02-20)
Molecular-secondary-ion mass spectrometry (SIMS) is a suitable method for the analysis of nonvolatile substances such as conjugated metabolites of drugs. We have developed a simple method for the direct SIMS measurement of conjugates following thin-layer chromatography without any extraction procedure.
P P Wickramanayake et al.
Biomedical mass spectrometry, 12(3), 127-133 (1985-03-01)
Mass spectra of a series of chloro- and nitrophenylglucuronides by liquid secondary ion (LSI) mass spectrometry were obtained. In the positive ion mode class characteristic fragmentations and adduct ions are observed only in the presence of alkali salt additives. No

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