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68903

Sigma-Aldrich

4-Methylumbelliferyl β-D-galactopyranoside-6-sulfate

galactose-6-sulfate sulphatase substrate, ≥90% (HPLC), powder

别名:

4-MU-Gal-6S sodium salt, 4-Methylumbelliferyl Beta-D-galactopyranoside-6-sulfate sodium salt, 4-Methylumbelliferyl Gal-6S sodium salt

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About This Item

经验公式（希尔记法）:
C16H17NaO11S
CAS号:
126938-14-5
分子量:
440.35
MDL號碼:
MFCD01861961
分類程式碼代碼:
12352204
PubChem物質ID:
329761212
NACRES:
NA.32

product name

4-Methylumbelliferyl β-D-galactopyranoside-6-sulfate, ≥90% (HPLC)

化驗

≥90% (HPLC)

形狀

powder

儲存溫度

−20°C

SMILES 字串

[Na+].CC1=CC(=O)Oc2cc(O[C@@H]3O[C@H](COS([O-])(=O)=O)[C@H](O)[C@H](O)[C@H]3O)ccc12

InChI

1S/C16H18O11S.Na/c1-7-4-12(17)26-10-5-8(2-3-9(7)10)25-16-15(20)14(19)13(18)11(27-16)6-24-28(21,22)23;/h2-5,11,13-16,18-20H,6H2,1H3,(H,21,22,23);/q;+1/p-1/t11-,13+,14+,15-,16-;/m1./s1

InChI 密鑰

KHTOBGQRIASILC-XNSOHGFJSA-M

應用

suitable as a fluorogenic substrate for galactose-6-sulfate sulphatase; fluorogenic substrate for the diagnosis of Morquio disease type A

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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O P van Diggelen et al.
Clinica chimica acta; international journal of clinical chemistry, 187(2), 131-139 (1990-02-28)
4-Methylumbelliferyl-beta-D-galactopyranoside-6-sulphate was synthesized and used for the determination of galactose-6-sulphate sulphatase activity. Fibroblasts and leucocytes from 12 different Morquio A patients, showed 0.0-2.7% of mean normal galactose-6-sulphate sulphatase activity. Heterozygotes showed intermediate activities. The enzymatic liberation of the fluorochrome from
H Zhao et al.
Prenatal diagnosis, 10(2), 85-91 (1990-02-01)
A new fluorogenic substrate, 4 methylumbelliferyl beta-D-6-sulphogalactoside, was used for the assay of galactose-6-sulphate sulphatase activity in chorionic villi, cultured villus cells, and amniocytes. The fluorometric assay is much more convenient than the conventional assay using radiolabelled, sulphated oligosaccharides. Both

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