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60178

Sigma-Aldrich

氰化钾

BioUltra, ≥98.0% (AT)

别名:

KCN, Potassium salt of hydrocyanic acid

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About This Item

线性分子式:
KCN
CAS号:
151-50-8
分子量:
65.12
Beilstein:
3593645
EC號碼:
205-792-3
MDL號碼:
MFCD00011397
分類程式碼代碼:
12352302
PubChem物質ID:
57651730
NACRES:
NA.25

生物源

synthetic

品質等級

200

產品線

BioUltra

化驗

≥98.0% (AT)

形狀

crystalline

雜質

insoluble matter, passes filter test

pH值

11.0-13.0 (25 °C, 1 M in H2O)

mp

634 °C (lit.)

溶解度

H2O: 1 M at 20 °C, clear, colorless

負離子痕跡

chloride (Cl-): ≤200 mg/kg
sulfate (SO42-): ≤400 mg/kg
sulfide (S2-): ≤5 mg/kg
thiocyanate (SCN-): ≤100 mg/kg

正離子痕跡

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤100 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤5000 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

&lambda ；

1 M in H2O

紫外吸收

λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03

SMILES 字串

[K]C#N

InChI

1S/CN.K/c1-2;

InChI 密鑰

YUZRZFQHUCKACF-UHFFFAOYSA-N

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應用

Potassium cyanide is use to inhibit oxidative phosphorylation reactions in a wide variety of biological systems and applications.

其他說明

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
Blocks electron transport to oxygen via cytochrome oxidase, hence employed in the determination of succinate dehydrogenase in submitochondrial particles by preventing substantial loss of succinate by electron flux to O2

訊號詞

Danger

危險分類

Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Met. Corr. 1 - STOT RE 1

標靶器官

Thyroid

安全危害

EUH032

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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EPR and other properties of succinate dehydrogenase.
T Ohnishi et al.
Methods in enzymology, 53, 483-495 (1978-01-01)
Pascaline Clerc et al.
Journal of bioenergetics and biomembranes, 39(2), 158-166 (2007-04-21)
We have studied the effect of nitric oxide (NO) and potassium cyanide (KCN) on oxidative phosphorylation efficiency. Concentrations of NO or KCN that decrease resting oxygen consumption by 10-20% increased oxidative phosphorylation efficiency in mitochondria oxidizing succinate or palmitoyl-L-carnitine, but
Yudong Wang et al.
The Journal of biological chemistry, 285(39), 29834-29841 (2010-07-29)
Fatty acid β-oxidation (FAO) and oxidative phosphorylation (OXPHOS) are key pathways involved in cellular energetics. Reducing equivalents from FAO enter OXPHOS at the level of complexes I and III. Genetic disorders of FAO and OXPHOS are among the most frequent
Mammalian succinate dehydrogenase.
B A Ackrell et al.
Methods in enzymology, 53, 466-483 (1978-01-01)
Takeshi Hatani et al.
Biochemical and biophysical research communications, 505(4), 1251-1256 (2018-10-20)
Many studies have shown the feasibility of in vivo cardiac transplantation of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) in animal experiments. However, nano-structural confirmation of the successful incorporation of the engrafted iPSC-CMs including electron microscopy (EM) has not been accomplished
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