推荐产品
生物源
mouse
品質等級
100
500
共軛
unconjugated
抗體表格
culture supernatant
抗體產品種類
primary antibodies
無性繁殖
SX53G8, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (427M-94)
vial of 0.5 mL concentrate (427M-95)
bottle of 1.0 mL predilute (427M-97)
vial of 1.0 mL concentrate (427M-96)
bottle of 7.0 mL predilute (427M-98)
製造商／商標名
Cell Marque®
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
同型
IgG1κ
控制
tonsil
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
nuclear
基因資訊
rat ... Cdkn1B(83571)
一般說明
p27 is a cyclin-dependent kinase inhibitor which regulates progression from G1 to S phase by binding and inhibiting cyclin-dependent kinases. Low p27 expression has been associated with unfavorable prognosis in renal cell carcinoma, colon carcinoma, small breast carcinomas, non-small-cell lung carcinoma, hepatocellular carcinoma, multiple myeloma, lymph node metastases in Papillary carcinoma of the Thyroid, and more aggressive phenotype in carcinoma of the cervix.
品質
 IVD |  IVD |  IVD |  RUO |
聯結
p27Kip1 Positive Control Slides, Product No. 427S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外觀
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
準備報告
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他說明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律資訊
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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历史批次信息供参考:
Mark L C Khoo et al.
The Journal of clinical endocrinology and metabolism, 87(4), 1814-1818 (2002-04-05)
Lymph node metastasis in papillary thyroid carcinoma increases the morbidity of treatment and the risk of local regional relapse and may also affect cure rates and survival. Factors that predict lymph node metastasis are, however, unclear. We analyzed 125 patients
Mark L C Khoo et al.
Archives of otolaryngology--head & neck surgery, 128(3), 253-257 (2002-03-12)
Papillary microcarcinomas (PMCs) of the thyroid (measuring less than 1 cm in maximum dimension) are extremely common incidental histologic findings, and most of these tumors are not considered clinically significant. However, rare PMCs behave aggressively and metastasize early, giving rise
Maria J Ribal et al.
Anticancer research, 23(6D), 5101-5106 (2004-02-26)
To assess the prognostic value of p27 protein expression in clinically localised prostate cancer with respect to biochemical recurrence after radical prostatectomy. Fifty-two patients (median age 63 years) with prostate cancer were treated by radical prostatectomy in an 18-month period.
Carolina Armengol et al.
Journal of hepatology, 38(5), 591-597 (2003-04-26)
Alterations in p27(Kip1) (p27) and cyclin E (cycE) expression are found in tumors and are related to poor prognosis. This study assesses the role of these cell cycle regulators in the development of recurrence after surgical resection in 46 cirrhotic
V Esposito et al.
Cancer research, 57(16), 3381-3385 (1997-08-15)
Despite its potential role as a tumor suppressor, p27 gene, a member of the Cip/Kip family of cyclin-dependent kinase inhibitor genes, has never been found mutated in human tumors. We investigated p27 protein expression in a series of 108 non-small
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