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Merck

Y0001980

叶酸杂质I

European Pharmacopoeia (EP) Reference Standard

别名:

叶酸, N-4-[(2-氨基-4-氧代-1,4-二氢-6-喋啶)甲氨基苯甲酰基]-L-谷氨酸, PteGlu, 维生素 M

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About This Item

经验公式(希尔记法):
C19H19N7O6
CAS号:
分子量:
441.40
Beilstein:
100781
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24

生物源

synthetic

等級

pharmaceutical primary standard

agency

EP

API 家族

folic acid

形狀

solid

製造商/商標名

EDQM

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O

InChI

1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

InChI 密鑰

OVBPIULPVIDEAO-LBPRGKRZSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Folic acid, a water-soluble B vitamin, is found in several food products. As it is not generated naturally in the human body, diet is one of the easiest ways to obtain it. It plays a crucial role in the biochemical synthesis and repair of DNA and is used in the management of megaloblastic anemias, neural tube defects such as anencephaly and spina bifida. Pharmaceutical drug forms of folic acid are desirable for supplementing its consumption through the diet.

應用

Folic acid for impurity I identification may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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其他客户在看

Folic acid hydrate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 6(9), 5662-5663 (2018)
A UV spectrophotometric method for the determination of folic acid in pharmaceutical tablets and dissolution tests
Matias R, et al.
Analytical Methods : Advancing Methods and Applications, 6(9), 3065-3071 (2014)
Flow injection chemiluminometric determination of folic acid in pharmaceutical formulations
Al-Warthan.AA
Analytical Sciences, 10(6), 919-922 (1994)

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