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Merck

SMB01363

Sigma-Aldrich

5α-Tetrahydrocortisol

≥95% (HPLC)

别名:

5α-Pregnane-3α,11β,17α,21-tetrol-20-one, α-THF, 5 alpha-Tetrahydrocortisol, ATHF, Allo-3a-tetrahydrocortisol, 3α,11β,17α,21-Tetrahydroxy-5α-pregnan-20-one, 3α,5α-Tetrahydrocortisol, Allopregnane-3α,11β,17α,21-tetrol-20-one, Allotetrahydrocortisol, Kendall’s compound C, Reichstein’s substance C

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About This Item

经验公式(希尔记法):
C21H34O5
CAS号:
分子量:
366.49
MDL號碼:
分類程式碼代碼:
51111800
NACRES:
NA.21

品質等級

化驗

≥95% (HPLC)

形狀

solid

成份

(3α,5α)-3,11,17,21-Tetrahydroxypregnan-20-one, ≤100%

包裝

pkg of 25 mg
pkg of 5 mg

顏色

white to beige

mp

244.5  °C

密度

1.205 g/cm3

儲存溫度

2-8°C

SMILES 字串

C[C@@]12CC[C@H](O)C[C@H]1CC[C@@H]3[C@H]4CC[C@@](O)(C(=O)CO)[C@@]4(C)C[C@@H](O)[C@@H]23

InChI

1S/C21H34O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-16,18,22-24,26H,3-11H2,1-2H3/t12-,13+,14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI 密鑰

AODPIQQILQLWGS-FDSHTENPSA-N

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一般說明

5α-Tetrahydrocortisol, also known as Allo-3a-tetrahydro cortisol (ATHC), a synthetic corticosteroid hormone derived from cortisol, is widely employed in biochemical and proteomics research. It is a metabolite of cortisol, a natural glucocorticoid that is used to treat various immune, inflammatory, and neoplastic conditions. In the context of medical diagnosis, a higher ratio of specific urinary metabolites can indicate the presence of Apparent Mineralocorticoid Excess (AME) syndrome, a rare form of hypertension linked to abnormalities in cortisol metabolism.

應用

5α-Tetrahydrocortisol finds application as a Biomarker in AME studies pertaining to Cortisol metabolism research

特點和優勢

  • Can be used in Metabolomics and Biochemical research
  • High-quality compound suitable for multiple research applications

其他說明

For additional information on our range of Biochemicals, please complete this form.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Aquatic Chronic 4 - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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