SMB01335

AFMK

≥95% (HPLC)

• 别名: AFMK, AFMKA, NSC-688263, NSC688263, N-[3-[2-(Formylamino)-5-methoxyphenyl]-3-oxopropyl]acetamide, NSC 688263
• 经验公式（希尔记法）: C₁₃H₁₆N₂O₄
• CAS号: 52450-38-1
• 分子量: 264.28
• MDL號碼: MFCD02683241
• 分類程式碼代碼: 12352116

属性

• 品質等級: 200
• 化驗: ≥95% (HPLC)
• 形狀: solid
• 儲存溫度: 2-8°C
• SMILES 字串: COc1ccc(NC=O)c(c1)C(=O)CCNC(C)=O
• InChI: 1S/C13H16N2O4/c1-9(17)14-6-5-13(18)11-7-10(19-2)3-4-12(11)15-8-16/h3-4,7-8H,5-6H2,1-2H3,(H,14,17)(H,15,16)
• InChI 密鑰: JYWNYMJKURVPFH-UHFFFAOYSA-N

说明

一般說明

Melatonin and its metabolites are being studied for their antioxidant properties and their protective effects against oxidative stress in both mammals and in plants. N¹-Acetyl-5-methoxykynuramine (AMK) and its direct precursor N¹-acetyl-N²-formyl-5-methoxykynuramine (AFMK) are two metabolites that contribute to the antioxidant properties of melatonin.

應用

Metabolomics research

生化／生理作用

AFMK is a melatonin metabolite first detected in rat brain; demonstrates antioxidant and free radical scavenging activities in several experimental models; inhibits LPS-mediated production of TNFα and IL-8 in neutrophils; useful tool in the study of melatonin metabolism.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301
• 防範說明: P264 - P270 - P301 + P310 - P405 - P501
• 危險分類: Acute Tox. 3 Oral
• 儲存類別代碼: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable