SMB00925

5,6-trans-vitamin D3

≥90% (HPLC)

• 别名: 5,6-trans-vitamin D3, (3b,5E,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol, calciol, cholecalciferol, colecalciferol
• 经验公式（希尔记法）: C₂₇H₄₄O
• CAS号: 22350-41-0
• 分子量: 384.64
• 分類程式碼代碼: 12352205

属性

• 品質等級: 100
• 化驗: ≥90% (HPLC)
• 形狀: solid
• 顏色: white to pale yellow
• 儲存溫度: −20°C
• InChI: 1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
• InChI 密鑰: QYSXJUFSXHHAJI-YRZJJWOYSA-N

说明

一般說明

Calciol is a hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D₃, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D₃), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D₃), the active hormone. It has a role as a human metabolite. It is a seco-cholestane, a hydroxy seco-steroid, a member of D₃ vitamins, a secondary alcohol and a steroid hormone.

Also known as 5,6-trans-Cholecalciferol, this compound is the major photoisomer of the Vitamin D3 analog and acts as a biologically active form of cholecalciferol (vitamin D). Vitamin D3 induces cell differentiation and prevents the proliferation of cancer cells. Additionally, 5,6-trans-Cholecalciferol activates calcium-dependent signaling pathways crucial for bone metabolism and the immune system. It is a versatile molecule with hypoglycemic and anti-inflammatory properties, making it applicable in immunology, oncology, metabolomics, and biochemical research.

應用

5,6-trans-vitamin D3 has been used:

• to study the effects of different derivatives of vitamin D3 on bone resorption
• to study the antiproliferative activity of photoisomers

特點和優勢

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

其他說明

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安全信息

• 象形圖: GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H301 - H330 - H372
• 防範說明: P301 + P310 + P330 - P304 + P340 + P310 - P314
• 危險分類: Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - STOT RE 1
• 儲存類別代碼: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable