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Merck

PHR1608

Supelco

Lactulose

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

Lactulose, 4-O-β-D-Galactopyranosyl-D-fructofuranose, 4-O-β-D-Galactopyranosyl-D-fructose

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About This Item

经验公式(希尔记法):
C12H22O11
CAS号:
分子量:
342.30
Beilstein:
93773
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to BP 210
traceable to Ph. Eur. L0130000
traceable to USP 1356803

API 家族

lactulose

CofA

current certificate can be downloaded

包裝

pkg of 1 g

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@](O)(CO)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11/c13-1-4-6(16)7(17)8(18)11(21-4)22-9-5(2-14)23-12(20,3-15)10(9)19/h4-11,13-20H,1-3H2/t4-,5-,6+,7+,8-,9-,10+,11+,12+/m1/s1

InChI 密鑰

JCQLYHFGKNRPGE-WJONTELPSA-N

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一般說明

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Lactulose is a disaccharide that finds immense applications in medicine, nutrition and dairy technology. It is utilized as a medicine in the treatment of portal systemic encephalopathy and chronic constipation.

應用

Lactulose may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAB7605 in the slot below. This is an example certificate only and may not be the lot that you receive.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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访问文档库

Chromatographic determination of lactulose
Martinez-Castro I, et al.
Chromatographia, 23(2), 132-136 (1987)
Use of an automated robotic system for the extraction and on-line high-performance liquid chromatographic analysis of pharmaceutical formulations
Van der Voorden EC, et al.
Chemometrics and Intelligent Laboratory Systems, 17(1), 129-135 (1992)
Kostan W Reisinger et al.
Journal of pediatric gastroenterology and nutrition, 59(6), 720-724 (2014-08-12)
The incidence of necrotizing enterocolitis (NEC) is higher in formula-fed babies than in breast-fed babies, which may be caused by breast-feeding-induced gut maturation. The effect of breast-feeding on gut maturation has been widely studied in animal models. This study aimed
A A Guerra-Ordaz et al.
Applied and environmental microbiology, 80(16), 4879-4886 (2014-06-08)
The potential of a prebiotic oligosaccharide lactulose, a probiotic strain of Lactobacillus plantarum, or their synbiotic combination to control postweaning colibacillosis in pigs was evaluated using an enterotoxigenic Escherichia coli (ETEC) K88 oral challenge. Seventy-two weanlings were fed four diets:
Jun Fang et al.
Journal of pharmaceutical sciences, 103(10), 3235-3243 (2014-07-22)
Bacteria of micrometer size could accumulate in tumor based on enhanced permeability and retention (EPR) effect. We report here Lactobacillus casei (L. casei), a nonpathogenic facultatively anaerobic bacterium, preferentially accumulated in tumor tissues after intravenously (i.v.) injection; at 24 h

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