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Merck

PHL82615

Oroxylin A

phyproof® Reference Substance

别名:

5,7-Dihydroxy-6-methoxy-2-phenyl-4H-1-benzopyran-4-one, 5,7-Dihydroxy-6-methoxyflavone;, 6-Methoxybaicalein;

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About This Item

经验公式(希尔记法):
C16H12O5
CAS号:
分子量:
284.26
MDL號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

primary reference standard

產品線

phyproof® Reference Substance

化驗

≥90.0% (HPLC)

製造商/商標名

PhytoLab

應用

food and beverages

形式

neat

SMILES 字串

COc1c(O)cc2OC(=CC(=O)c2c1O)c3ccccc3

InChI

1S/C16H12O5/c1-20-16-11(18)8-13-14(15(16)19)10(17)7-12(21-13)9-5-3-2-4-6-9/h2-8,18-19H,1H3

InChI 密鑰

LKOJGSWUMISDOF-UHFFFAOYSA-N

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一般說明

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

生化/生理作用

Oroxylin A is a flavonoid isolated from Scutellaria baicalensis, which is one of the most important medicinal herbs in traditional Korean/Chinese/Japanese medicine. The amelioration of Abeta(25-35) peptide-induced memory impairment by oroxylin A is believed to be mediated via the GABAergic neurotransmitter system after a single administration, or by reductions in Abeta(25-35) peptide-induced astrocyte and microglia activations, iNOS expression, lipid peroxidation, and increased cholinergic neurotransmission after subchronic administration.

法律資訊

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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Min Shen et al.
International immunopharmacology, 85, 106637-106637 (2020-06-09)
More and more evidence showed that autophagy is an inflammation-related defense mechanism against a variety of diseases including liver fibrosis. However, the essential mechanisms remain poorly understood. In this study, we sought to elucidate the impact of Oroxylin A on

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