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一般說明
IV型胶原酶(Cls IV)属于哺乳动物细胞外中性金属蛋白酶家族成员。消化基底膜的主要组成成分——IV型胶原蛋白。
该产品与Biochrom GmbH部件号C4-22和C4-28相同。由胶原酶、梭菌蛋白酶混合而成的酶，具有胰蛋白酶和蛋白水解活性。推荐用于分离朗格汉斯岛。比活度为每毫克粉末物质125至250 Mandl单位。
應用
IV型胶原酶(Cls IV)用途：
- 作为杜氏改良Eagle培养基(DMEM)/F12组分，用于消化来自体外受精(IVF)患者的子宮內膜标本
- 用于胶原酶肝脏灌流法分离大鼠肝细胞
- 用于分离大鼠肾小球内皮细胞(GEndCs)
从最新的版本中选择一种：
Hyun-Jeong Cho et al.
Biological & pharmaceutical bulletin, 28(8), 1418-1423 (2005-08-05)
Microsomal triglyceride (TG) transfer protein (MTP) is involved in the secretion of TG-rich very low-density lipoprotein (VLDL), a process which leads to the generation of hypertriglyceridemia and atherosclerosis. We investigated the possible role of Ca(2+) on MTP activity in hepatocytes.
Dan-Pei Li et al.
Nature communications, 14(1), 4436-4436 (2023-07-23)
Inhibition of immunocyte infiltration and activation has been suggested to effectively ameliorate nonalcoholic steatohepatitis (NASH). Paired immunoglobulin-like receptor B (PirB) and its human ortholog receptor, leukocyte immunoglobulin-like receptor B (LILRB2), are immune-inhibitory receptors. However, their role in NASH pathogenesis is
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