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Merck

82270

Sigma-Aldrich

1,2-二氯丙烷

99%

别名:

二氯化丙烯

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About This Item

线性分子式:
CH3CHClCH2Cl
CAS号:
分子量:
112.99
Beilstein:
1718880
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

蒸汽密度

3.89 (vs air)

品質等級

蒸汽壓力

40 mmHg ( 19.4 °C)

化驗

99%

形狀

liquid

自燃溫度

1035 °F

expl. lim.

14.5 %

折射率

n20/D 1.439 (lit.)
n20/D 1.439

bp

95-96 °C (lit.)

mp

−100 °C (lit.)

密度

1.156 g/mL at 25 °C (lit.)

SMILES 字串

CC(Cl)CCl

InChI

1S/C3H6Cl2/c1-3(5)2-4/h3H,2H2,1H3

InChI 密鑰

KNKRKFALVUDBJE-UHFFFAOYSA-N

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應用

1,2-二氯丙烷可用作合成以下物质的结构单元:
  • 在乙磺酸钠的参与下,与二硫化碳和活性亚甲基化合物通过一锅反应合成的2-烯基-1,3-二噻茂烷衍生物。      
  • β与硫醇的可控脱氯偶联反应制备的氯丙基硫化合物。      
  • 在磷叶立德催化的条件下,与 β-酮基硫代酰胺通过[3+2]和[3+3]环化反应制备的噻唑烷和1,3-噻嗪烷衍生物。

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

59.0 °F - closed cup

閃點(°C)

15.0 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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分析证书(COA)

Lot/Batch Number

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访问文档库

Monish Arbaz Ansari et al.
Organic & biomolecular chemistry, 17(41), 9151-9162 (2019-10-09)
Phosphonium ylides are being reported here as a catalyst for the formation of thiazolidines and 1,3-thiazinanes from β-ketothioamides (which act as a three atom N, C, and S synthon) with dihaloalkanes via [3 + 2] and [3 + 3] annulations
Synthesis of some 2-ylidene-1, 3-dithiolanes
Lipin KV, et al.
Russ. J. Org. Chem., 53(1), 147-149 (2017)
H D Kirk et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 28(1), 18-26 (1995-11-01)
1,2-Dichloropropane (PDC) was evaluated for its potential to cause embryonal/fetal toxicity and teratogenicity in pregnant rats and rabbits. PDC was administered via oral gavage at dose levels of 0, 10, 30, or 125 mg/kg/day on Days 6 through 15 of
A Odinecs et al.
Renal failure, 17(5), 517-524 (1995-09-01)
The contribution of testosterone to the nephrotoxic effects of 1,2-dichloropropane (DCP) was assessed by a series of castration and sex hormone replacement experiments on Wistar rats. The nephrotoxic action of DCP was evaluated by measuring the accumulation of organic anion
[Determination of 1, 2 propylene dichloride in air in working places].
Wei Chen et al.
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 24(7), 440-441 (2006-08-08)

实验方案

US EPA Method TO-17: GC Analysis of Volatiles on VOCOL® after Collection/Desorption using Air Toxics Tube

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