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Merck

78697

Supelco

甲基磺酸甲酯

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

别名:

甲磺酸甲酯

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About This Item

线性分子式:
CH3SO3CH3
CAS号:
分子量:
110.13
Beilstein:
1098586
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
TraceCERT®

品質等級

產品線

TraceCERT®

儲存期限

limited shelf life, expiry date on the label

製造商/商標名

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

技術

HPLC: suitable
gas chromatography (GC): suitable

折射率

n20/D 1.414 (lit.)

bp

202-203 °C (lit.)

密度

1.3 g/mL at 25 °C (lit.)

應用

environmental
pharmaceutical

格式

neat

儲存溫度

2-8°C

SMILES 字串

COS(C)(=O)=O

InChI

1S/C2H6O3S/c1-5-6(2,3)4/h1-2H3

InChI 密鑰

MBABOKRGFJTBAE-UHFFFAOYSA-N

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一般說明

该认证标准物质(CRM)根据ISO/IEC 17025ISO 17034进行生产和认证。该CRM可追溯到来自NMI的原材料,如 NIST或NMIJ。
证书上给出了定量核磁共振法认证的内容,包括不确定性和失效日期。
请访问http://www.sigma-aldrich.com下载您的证书。
该认证标准物质(CRM)根据ISO/IEC 17025和ISO 17034进行生产和认证。该CRM可追溯来自NMI的原始材料,如NIST或NMIJ。NMR定量信息已包括在认证内容中。证书上已给出不确定性和失效日期。请在http://www.sigma-aldrich.com下载您的证书。

甲磺酸甲酯属于烷基磺酸酯类,是潜在的基因毒性杂质 (GTI)。

應用

有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务。
甲磺酸甲酯可用作认证标准物质,用于通过气相色谱-三重四级杆质谱联用法定量检测药物制剂中的分析物。

包裝

无底玻璃瓶。内含物在插入的融合锥体内。

原則

DNA 加合物;优先地将甲基加合到 DNA 的 7-鸟嘌呤,也可加合到 3-腺嘌呤和 3-鸟嘌呤。

推薦產品

在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析(使用数字化外标)。可查看该物质的NMR谱图,只需点击几次鼠标,就能进行在线样品比对。欢迎点击了解更多,开启免费试用之旅。

法律資訊

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Inhalation

標靶器官

Lungs

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

219.2 °F - closed cup

閃點(°C)

104 °C - closed cup


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Development and validation of a sensitive method for alkyl sulfonate genotoxic impurities determination in drug substances using gas chromatography coupled to triple quadrupole mass spectrometry
Liu Z, et al.
Journal of Pharmaceutical and Biomedical Analysis, 168(3), 23-29 (2019)
Stephanie Jungmichel et al.
Molecular cell, 52(2), 272-285 (2013-09-24)
Poly(ADP-ribos)ylation (PARylation) is a reversible posttranslational modification found in higher eukaryotes. However, little is known about PARylation acceptor proteins. Here, we describe a sensitive proteomics approach based on high-accuracy quantitative mass spectrometry for the identification of PARylated proteins induced under
Nicolas Dénervaud et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(39), 15842-15847 (2013-09-11)
Observing cellular responses to perturbations is central to generating and testing hypotheses in biology. We developed a massively parallel microchemostat array capable of growing and observing 1,152 yeast-GFP strains on the single-cell level with 20 min time resolution. We measured
Mukul R Jain et al.
Cancer chemotherapy and pharmacology, 82(4), 635-647 (2018-07-27)
Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme involved in the detection and repair of DNA damage. Studies have shown that inhibition of PARP and Tankyrase (TNKS) has significant antitumor effect in several types of cancers including BRCA-negative breast cancers. Identification
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Toxicology in vitro : an international journal published in association with BIBRA, 27(2), 768-773 (2012-12-25)
A serious limitation of the conventional comet assay (single cell gel electrophoresis) is the restriction on the number of samples that can be processed in one experiment, imposed by the size of the electrophoresis platform. One approach to increasing throughput

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