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Merck

410217

Sigma-Aldrich

2′,7′-二氯荧光素

ACS reagent

别名:

二氯荧光素;荧光素27

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About This Item

经验公式(希尔记法):
C20H10Cl2O5
CAS号:
分子量:
401.20
Beilstein:
58009
EC號碼:
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.47

等級

ACS reagent

品質等級

形狀

powder

顏色

orange to red-brown, powder

mp

280 °C (dec.) (lit.)

溶解度

alcohol: passes test

密度

0.790 g/cm3

λmax

509 nm

適合性

passes test for adsorption indicator

應用

diagnostic assay manufacturing
hematology
histology

儲存溫度

room temp

SMILES 字串

Oc1cc2Oc3cc(O)c(Cl)cc3C4(OC(=O)c5ccccc45)c2cc1Cl

InChI

1S/C20H10Cl2O5/c21-13-5-11-17(7-15(13)23)26-18-8-16(24)14(22)6-12(18)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,23-24H

InChI 密鑰

VFNKZQNIXUFLBC-UHFFFAOYSA-N

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一般說明

2′,7′-二氢荧光素是一种氧化敏感荧光探针。

應用

2′,7′-二氯荧光素已用于测量细胞中ROS(活性氧)的形成。 它已被用作荧光底物,以研究唾液样本及颌下腺提取物的过氧化物酶的活性。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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M-C Chang et al.
Journal of periodontal research, 48(1), 66-73 (2012-07-28)
Short-chain fatty acids, such as butyric acid and propionic acid, are metabolic by-products generated by periodontal microflora such as Porphyromonas gingivalis, and contribute to the pathogenesis of periodontitis. However, the effects of butyrate on the biological activities of gingival fibroblasts
Gyorgy Hajas et al.
Free radical biology & medicine, 52(4), 749-756 (2011-12-27)
8-Oxo-7,8-dihydroguanine is one the most abundant base lesions in pro- and eukaryotic DNA. In mammalian cells, it is excised by the 8-oxoguanine DNA glycosylase (OGG1) during DNA base-excision repair, and the generated free 8-oxoG base is one of the DNA-derived
Andréa G K Ferreira et al.
Journal of cellular biochemistry, 113(1), 174-183 (2011-09-02)
The present study investigated the effects of chronic hyperprolinemia on oxidative and metabolic status in liver and serum of rats. Wistar rats received daily subcutaneous injections of proline from their 6th to 28th day of life. Twelve hours after the
L Foucaud et al.
Toxicology in vitro : an international journal published in association with BIBRA, 24(6), 1512-1520 (2010-07-20)
The aim of this study was to investigate whether carbon black (CB) nanoparticles might induce toxicity to monocytic cells in vitro via an oxidative stress mechanism involving formation of the lipid peroxidation product 4-hydroxynonenal (4-HNE) and the subsequent role of
Olga N Pakhomova et al.
Archives of biochemistry and biophysics, 527(1), 55-64 (2012-08-23)
Nanosecond pulsed electric field (nsPEF) is a novel modality for permeabilization of membranous structures and intracellular delivery of xenobiotics. We hypothesized that oxidative effects of nsPEF could be a separate primary mechanism responsible for bioeffects. ROS production in cultured cells

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