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Merck

37919

Supelco

脱水四环素 盐酸盐

VETRANAL®, analytical standard

别名:

(4S,4aS,12aS)-4-(二甲基氨基)-1,4,4a,5,12,12a-六氢-3,10,11,12a-四羟基-6-甲基-1,12-二氧-2-萘并羧酰胺 单盐酸盐

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About This Item

经验公式(希尔记法):
C22H22N2O7 · HCl
CAS号:
分子量:
462.88
Beilstein:
4228856
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

agency

EPA 1694

產品線

VETRANAL®

儲存期限

limited shelf life, expiry date on the label

儲存條件

under inert gas

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

clinical testing

格式

neat

SMILES 字串

Cl[H].[H][C@@]12Cc3c(C)c4cccc(O)c4c(O)c3C(=O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C

InChI

1S/C22H22N2O7.ClH/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28;/h4-6,11,16,25-27,31H,7H2,1-3H3,(H2,23,30);1H/t11-,16-,22-;/m0./s1

InChI 密鑰

XBSQEFHDCDFNJU-WPJNXPDPSA-N

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一般說明

脱水四环素(ATC)是盐酸四环素的降解产物,在动物育种中广泛用作抗生素。

應用

分析标准品可用于:
  • 通过太赫兹(THz)光谱-温度依赖性技术定量和定性分析抗生素、 盐酸四环素和其三种主要代谢产物。
  • 通过共振拉曼光谱技术同时分析药物制剂中的盐酸四环素及降解产物,研究应激诱导的药物稳定性。
  • 开发和验证液相色谱-串联质谱(LC-MS/MS)方法,测定蜂蜜样本中21种用作兽药的抗生素残留。
  • 通过液液微萃取(DLLME)及超高压液相色谱(UHPLC)-可调谐紫外检测(TUV)技术测定各种环境水样中的8种四环素抗生素。

其他說明

有关合适的仪器技术的更多信息,请参阅产品′的检验报告。想要获得更多支持,请联系技术服务部。

法律資訊

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

Lot/Batch Number

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Susceptibility of Escherichia coli and Enterococcus faecium isolated from pigs and broiler chickens to tetracycline degradation products and distribution of tetracycline resistance determinants in E. coli from food animals
Sengelov G, et al.
Veterinary Microbiology, 95, 91-101 (2003)
Marcus Resch et al.
Nucleic acids research, 36(13), 4390-4401 (2008-07-01)
Today's proteome is the result of innumerous gene duplication, mutagenesis, drift and selection processes. Whereas random mutagenesis introduces predominantly only gradual changes in protein function, a case can be made that an abrupt switch in function caused by single amino
Wenjun Zhang et al.
Journal of the American Chemical Society, 130(19), 6068-6069 (2008-04-22)
The cyclohexenone ring A of tetracyclines exhibits unique structural features not observed among other aromatic polyketides. These substitutions include the C2 primary amide, C4 dimethylamine, and the C12a tertiary alcohol. Here we report the identification and reconstitution of the minimum
Marta Gratacós-Cubarsí et al.
Journal of agricultural and food chemistry, 55(11), 4610-4616 (2007-05-10)
Tetracycline (TC) and 4-epitetracycline (4eTC) degradation, as well as anhydrotetracycline (ATC) and 4-epianhydrotetracycline (4eATC) formation, has been evaluated in thermally treated chicken breast, pig loin, and pig loin with added back-fat. Samples containing TC and 4eTC residues were submitted to
Prasanna Bhomkar et al.
PloS one, 6(11), e27559-e27559 (2011-12-02)
Synthetic biology is an emerging branch of molecular biology that uses synthetic genetic constructs to create man-made cells or organisms that are capable of performing novel and/or useful applications. Using a synthetic chemically sensitive genetic toggle switch to activate appropriate

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