31550

2,3-丁二酮一肟

for spectrophotometric det. of urea, ≥99.0%

• 别名: BDM, 二乙酰一肟, 联乙酰一肟
• 线性分子式: CH₃C(=NOH)COCH₃
• CAS号: 57-71-6
• 分子量: 101.10
• Beilstein: 605582
• EC號碼: 200-348-5
• MDL號碼: MFCD00002116
• 分類程式碼代碼: 41116105
• PubChem物質ID: 329753805
• NACRES: NA.21

属性

• 品質等級: 100
• 化驗: ≥98.0% (N); ≥99.0%
• 形狀: solid
• 品質: for spectrophotometric det. of urea
• 技術: UV/Vis spectroscopy: suitable
• 燃燒殘留物: ≤0.05% (as SO₄)
• bp: 185-186 °C (lit.)
• mp: 75-76 °C; 75-78 °C (lit.)
• SMILES 字串: CC(=O)\C(C)=N\O
• InChI: 1S/C4H7NO2/c1-3(5-7)4(2)6/h7H,1-2H3/b5-3+
• InChI 密鑰: FSEUPUDHEBLWJY-HWKANZROSA-N

说明

一般說明

2,3-丁二酮单肟 (BDM) 又名二乙酰单肟，它也是一种亲核剂，它能使有机磷酸酯中毒的乙酰胆碱酯酶去磷酸化。它也是骨骼肌肌球蛋白 II 的典型的非竞争性抑制剂，抑制化学和运动活性。

應用

• A novel method to extend viability and functionality of living heart slices.: This research introduces a novel application of 2,3-Butanedione monoxime for prolonging the functional lifespan of cardiac tissue samples in experimental settings, offering insights into cardiac biology and potential therapeutic targets (Ross et al., 2023).


• Molecular Mechanisms of Deregulation of Muscle Contractility Caused by the R168H Mutation in TPM3 and Its Attenuation by Therapeutic Agents.: The study utilizes 2,3-Butanedione monoxime to investigate the molecular pathways affected by genetic mutations in muscle contractility, contributing to the understanding of muscle disorders and their management (Karpicheva et al., 2023).


• Generation of myocyte agonal Ca(2+) waves and contraction bands in perfused rat hearts following irreversible membrane permeabilisation.: Research employing 2,3-Butanedione monoxime investigates its role in inducing specific cellular events in cardiac cells under stress, highlighting its potential in studies of heart disease mechanisms and therapies (Morishita et al., 2023).

分析報告

溶解度：
0.5g 本品加入到 10mL 水或者 10mL 乙醇中，可以形成澄清溶液。
灵敏性测试：
将溶于 3mL 水和 5mL 浓盐酸的 0.05mg 尿素与 3% 的二乙酰单肟水溶液在水浴上加热 10 分钟，颜色呈淡黄色。

其他說明

用于尿素和脲基化合物比色测定的试剂 ；钴 (II)、镍 (II)、钯 (II) 和铼 (VII) 的光谱分析试剂 ；镍 (Ⅱ) 重量法测定用试剂

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)