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生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
6F3.1, monoclonal
物種活性
human
技術
immunohistochemistry: suitable
western blot: suitable
同型
IgG2aκ
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... RORC (6097)
一般說明
类视黄醇相关的孤儿受体-γ t(RORγT)是属于核激素受体家族的两种RORγ亚型之一,并包含单个核受体DNA结合结构域。RORγT是TNFDF6/FasL表达和IL2的T细胞产生的负调节剂。RORγT的上调是TH17细胞分化的要求。TGF-β’s与Foxp3的相互作用诱导了RORγT的抑制。主要在未成熟的胸腺细胞中观察到表达,并且在胎儿发育过程中,仅在淋巴诱导(LTi)细胞中发现表达。
免疫原
GST标记的重组蛋白,对应于人RORγt。
應用
免疫组织化学分析:该抗体以1:50稀释度在正常人肝组织中检测到RORγT。
研究子类别
炎症 & 自身免疫机制
炎症 & 自身免疫机制
研究类别
炎症 & 免疫学
炎症 & 免疫学
经验证,该抗RORγT抗体(克隆6F3.1)可用于WB、IH中检测RORγT。
品質
通过蛋白质印迹法在T47D细胞裂解物中进行评估。
蛋白质印迹分析:1 µg/mL的该抗体在10 µg的T47D细胞裂解物中检测到RORγT。
蛋白质印迹分析:1 µg/mL的该抗体在10 µg的T47D细胞裂解物中检测到RORγT。
標靶描述
观测分子量〜55 kDa。在一些细胞裂解物中可观察到~55 kDa和~58 kDa的两种亚型。
外觀
形式:纯化
纯化的小鼠单克隆IgG2aκ,溶于含0.1 M Tris-甘氨酸(pH 7.4)、150 mM NaCl和0.05%叠氮化钠的缓冲液中。
纯化蛋白G
儲存和穩定性
自接收之日起,在2-8°C下可稳定保存1年。
分析報告
对照
T47D细胞裂解物
T47D细胞裂解物
其他說明
浓度:关于批次特定浓度请参见检验报告。
免責聲明
除非我们的目录或产品随附的其他公司文件中另有说明,否则我们的产品预期仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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