MABF73

Anti-Tim3 Antibody, clone 5D12

clone 5D12, from mouse

• 别名: Hepatitis A virus cellular receptor 2 homolog, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell membrane protein 3, TIMD-3, TIM-3
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 5D12, monoclonal
• 物種活性: mouse
• 技術: flow cytometry: suitable
• 同型: IgG1κ
• NCBI登錄號: NP_599011
• UniProt登錄號: Q8VIM0
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: mouse ... Havcr2(171285)

说明

一般說明

As a member of the T cell immunoglobulin and mucin domain (TIM) family, Tim-3 is reported to promote or terminate Th1 immunity and is thought to influence a range of inflammatory conditions. It is constitutively expressed in a subset of murine IFNgamma-secreting Th1 cells, but not Th2 cells, in both human and mice. Additionally, Tim-3 is expressed dendritic cells, and by a subset of CD4+ cells where its levels of expression increase upon anti-CD3/28 stimulation. This molecule is also be highly expressed in in vitro polarized Th1 cells, and at lower levels in Th17 cells. Tim-3 is known to synergize with Toll-like receptors (TLRs) and is thought to regulate Th1 and Th17 cytokine secretion.

免疫原

Recombinant protein corresponding to full length mouse Tim3.

應用

Anti-Tim3 Antibody, clone 5D12 is an antibody against Tim3 for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

品質

Evaluated by Flow Cytometry in RAW264.7 cells.

Flow Cytometry Analysis: A 1:50 dilution of this antibody detected Tim3 in RAW264.7 cells.

標靶描述

31 kDa calculated

外觀

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
RAW264.7 cells

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable