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Key Documents

MAB5424

Sigma-Aldrich

Anti-Prion Protein Antibody

Chemicon®, from mouse

别名:

PrP, CD230

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

monoclonal

物種活性

sheep, mouse, mule deer, bovine, elk

製造商/商標名

Chemicon®

技術

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

同型

IgG1

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... PRNP(5621)

特異性

Reacts with prion protein (PrP) from bovine, sheep, mule deer, elk and mouse. The monoclonal recognizes both protease sensitive and protease resistant forms of PrP (after denaturing).

免疫原

Recombinant PrP amino acids 23-237.

應用

Anti-Prion Protein Antibody is an antibody against Prion Protein for use in ELISA, WB, IH.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Western blot: 1:50,000-1:200,000

Immunohistochemistry: 1:100-1:500. Epitope must be re-exposed in fixed tissue by pretreatment of tissue using one of the following procedures:

a. formic acid for 10 minutes at room temperature

b. hydrolytic autoclaving

c. heat induced epitope retrieval

ELISA: 1:20,000-1:50,000

Optimal working dilutions must be determined by end user.

外觀

Format: Purified
Purified immunoglobulin. Liquid in PBS. Contains no preservative.

儲存和穩定性

Maintain at -20°C to -70°C in undiluted aliquots for up to 6 months after date of receipt.

Avoid repeated freeze/thaw cycles.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Christopher J Silva
Prion, 6(2), 163-173 (2012-03-23)
PrP(Sc) is an infectious protein. The only experimentally verified difference between PrP(Sc) and its normal cellular isoform (PrP(C)) is conformational. This work describes an approach to determining the presence of surface exposed or sequestered amino acids present in the PrP(Sc)

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