推荐产品
生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
41-1E5, monoclonal
物種活性
rabbit, human
製造商／商標名
Chemicon®
技術
ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
同型
IgG2aκ
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... MMP1(4312)
特異性
Specifically reacts with precursor and active forms of human MMP-1.
免疫原
Epitope: a.a. 332-350 hMMP1
Syntheic peptide aa332-350 of hMMP-1
應用
Anti-MMP-1 Antibody, a.a. 332-350 hMMP1, clone 41-1E5 detects level of MMP-1 & has been published & validated for use in ELISA, IH(P) & WB.
Immunoblotting:
Immunohistochemistry on PLP fixed, paraffin-embedded tissues 5-20μg/ml. PLP fixation required for best results. Antibody also reacts with frozen tissues. Reactivity on tradional formalin fixed tissue is poor. Microwave antigen retrieval is recommended
ElA
Immunohistochemistry on PLP fixed, paraffin-embedded tissues 5-20μg/ml. PLP fixation required for best results. Antibody also reacts with frozen tissues. Reactivity on tradional formalin fixed tissue is poor. Microwave antigen retrieval is recommended
ElA
標靶描述
52 kDa
聯結
Replaces: 04-1122
外觀
Format: Purified
Liquid in 0.1 M Na-Phosphate buffer, pH 7.0 containing 2% protease free bovine Serum albumin.
分析報告
Control
Cervical carcinoma
SKBr-3 cell lysate
Cervical carcinoma
SKBr-3 cell lysate
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Akt inhibition up-regulates MMP1 through a CCN2-dependent pathway in human dermal fibroblasts.
Andreea M Bujor,Sashidar Nakerakanti,Erin Morris,Faye N Hant,Maria Trojanowska
Experimental Dermatology null
Immunohistochemical demonstration of collagenase and tissue inhibitor of metalloproteinases (TIMP) in synovial lining cells of rheumatoid synovium
Okada, Y. et al.
Virchows Archiv. B, Cell Pathology Including Molecular Pathology, 59, 305-312 (1990)
Cdc42 downregulates MMP-1 expression by inhibiting the ERK1/2 pathway.
Deroanne, CF; Hamelryckx, D; Ho, TT; Lambert, CA; Catroux, P; Lapiere, CM; Nusgens, BV
Journal of Cell Science null
A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 1 (interstitial collagenase) using monoclonal antibodies
Zhang, J. et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 219, 1-14 (1993)
Carine Strup-Perrot et al.
World journal of gastroenterology, 11(40), 6312-6321 (2006-01-19)
To investigate their expression and activity in the rat ileum after exposure to ionizing radiation along with that of the cellular effectors and molecular mediators involved in the regulation of MMPs. Rats were exposed to a single 10-Gy dose of
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