推荐产品
生物源
mouse
抗體表格
ascites fluid
抗體產品種類
primary antibodies
無性繁殖
D1-4G2-4-15, monoclonal
物種活性
human
製造商／商標名
Chemicon®
技術
immunofluorescence: suitable
同型
IgG1
IgG2a
運輸包裝
dry ice
一般說明
黄病毒科的病毒是人类和兽医学中重要的节肢动物传播的病毒。它们通过蚊子和蜱传播，通常在自然界中维持在传播周期中。它们在人类中产生广泛的临床反应，从无症状的感染到暴发性脑炎或出血热。已知存在近60种黄病毒，但许多尚未证明会引起人类疾病。
特異性
识别黄病毒组特异性抗原（登革热病毒、西尼罗河病毒、日本乙型脑炎、黄热病病毒、寨卡病毒等）。它与蛋白E结构域II末端的融合环结合。
免疫原
登革热病毒2型抗原
應用
&已发表抗黄病毒组抗原抗体，克隆D1-4G2-4-15可检测黄病毒组抗原水平，&经验证可用于IF。
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Qian Chen et al.
Nature communications, 11(1), 2967-2967 (2020-06-13)
The recent outbreak of Zika virus (ZIKV) was associated with birth defects and pregnancy loss when maternal infection occurs in early pregnancy, but specific mechanisms driving placental insufficiency and subsequent ZIKV-mediated pathogenesis remain unclear. Here we show, using large scale
V Haridas et al.
PLoS neglected tropical diseases, 7(1), e2005-e2005 (2013-01-26)
Japanese encephalitis virus (JEV) is a major cause of viral encephalitis in South and South-East Asia. Lack of antivirals and non-availability of affordable vaccines in these endemic areas are a major setback in combating JEV and other closely related viruses
A Viral Polymerase Inhibitor Reduces Zika Virus Replication in the Reproductive Organs of Male Mice.
Sofie Jacobs et al.
International journal of molecular sciences, 20(9) (2019-04-30)
In humans, Zika virus and viral RNA have been detected in semen up to 2.2 months and 6 months post infection (pi), respectively. Although the contribution of sexual transmission to the spread of ZIKV is too low to sustain an
Andreas S Puschnik et al.
Cell reports, 21(11), 3032-3039 (2017-12-16)
The mosquito-borne flaviviruses include important human pathogens such as dengue, Zika, West Nile, and yellow fever viruses, which pose a serious threat for global health. Recent genetic screens identified endoplasmic reticulum (ER)-membrane multiprotein complexes, including the oligosaccharyltransferase (OST) complex, as
José A Aguilar-Briseño et al.
Nature communications, 11(1), 3177-3177 (2020-06-25)
Vascular permeability and plasma leakage are immune-pathologies of severe dengue virus (DENV) infection, but the mechanisms underlying the exacerbated inflammation during DENV pathogenesis are unclear. Here, we demonstrate that TLR2, together with its co-receptors CD14 and TLR6, is an innate
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