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Merck
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Key Documents

EZRMGH

Millipore

Rat/Mouse Growth Hormone ELISA Kit

measures and quantifies GH levels in 10 μL serum, plasma or cell culture supernatent

别名:

Growth hormone, Somatotrophin

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About This Item

分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.32

product name

大鼠/小鼠生长激素ELISA, This Rat/Mouse Growth Hormone ELISA is used to measure & quantify Growth Hormone levels in Metabolism & Endocrine & Cell Signaling research.

品質等級

200

物種活性

rat, mouse

包裝

kit of 1 × 96 wells

參數

10 μL sample volume (4hr assay)

assay range

accuracy: 96-101%
linearity: 97-118%
sensitivity: 0.07 ng/mL
(10 μl sample size)
standard curve range: 0.07-50 ng/mL

技術

ELISA: suitable

輸入

sample type serum
sample type cell culture supernatant
sample type plasma (K2 EDTA)

UniProt登錄號

P01244
P06880

應用

research use

檢測方法

colorimetric (450nm/590nm)

運輸包裝

wet ice

儲存溫度

2-8°C

一般說明

生长激素（GH）是一种23 kDa的循环垂体激素，大鼠GH在其GH序列中与小鼠GH具有约97%的同源性，与人蛋白具有约65%的同源性。生长激素的主要作用对象为中枢神经系统。在动物模型中，该激素针对神经退化性刺激产生神经保护作用，并防止缺氧缺血性脑损伤的神经损失。因此，随老化而出现的生长激素水平下降影响大脑功能，并导致记忆和认知损害。该大鼠/小鼠生长激素ELISA用于在代谢&内分泌&细胞信号转导研究中测量&定量生长激素水平。

應用

大鼠/小鼠生长激素ELISA已被用于测量或量化小鼠血液样品、异种移植物模型和血浆样品中的生长激素水平。

其他說明

室温3.5小时，10 μl血清、血浆或组织培养基

象形圖

Skull and crossbonesCorrosion
GHS06,GHS05

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

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Naomi Morozumi et al.
Peptides, 32(5), 1001-1007 (2011-02-05)
Ghrelin is an endogenous ligand for growth hormone secretagogue receptor 1a (GHS-R1a), and consists of 28 amino acid residues with octanoyl modification at Ser(3). The previous studies have revealed that N-terminal part of ghrelin including modified Ser(3) is the active
Reproductive dysfunction and decreased gnRH neurogenesis in a Mouse Model of cHARGE syndrome.
Layman WS, Hurd EA, Martin DM
Human Molecular Genetics null
Iñigo Azcoitia et al.
Neurobiology of aging, 26(5), 697-703 (2005-02-15)
Decline of growth hormone (GH) with aging is associated to memory and cognitive alterations. In this study, the number of neurons in the hilus of the dentate gyrus has been assessed in male and female Wistar rats at 3, 6
Supriya Sen et al.
Nature communications, 4, 1336-1336 (2013-01-10)
SR family RNA binding proteins regulate splicing of nascent RNAs in vitro but their physiological role in vivo is largely unexplored, as genetic deletion of many SR protein genes results in embryonic lethality. Here we show that SRSF3HKO mice carrying
Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons.
Briggs DI, Enriori PJ, Lemus MB, Cowley MA, Andrews ZB
Endocrinology null

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