推荐产品
生物源
goat
品質等級
共軛
peroxidase conjugate
抗體表格
F(ab′)2 fragment of affinity isolated antibody
抗體產品種類
secondary antibodies
無性繁殖
polyclonal
物種活性
human
製造商／商標名
Chemicon®
技術
ELISA: suitable
western blot: suitable
運輸包裝
wet ice
目標翻譯後修改
unmodified
一般說明
免疫球蛋白G（IgG）是在人血清中发现的最常见的抗体同型。它以IgG1、IgG2、IgG3和IgG4四种亚型存在。IgG结构包含四条多肽链，由两条相同的重（H）链和两条相同的λ轻（L）链组成。这些链通过二硫键相互连接。IgG由B细胞产生。
免疫原
人 IgG
應用
羊抗人IgG抗体Fc，HRP偶联物已用于酶联免疫吸附试验（ELISA）（1:3,000）。
还可用于：
还可用于：
- 酶免疫测试（EIA），OPD：1:5,000-1:100,000
- 免疫组织化学1:500-1:5,000
- 蛋白质印迹
生化／生理作用
免疫球蛋白G（IgG）与抗体依赖性细胞介导的细胞毒性（ADCC）有关。它有助于激活补体系统的经典途径。它中和病毒颗粒和毒素。 母体IgG通过胎盘传递给胎儿，这对保护新生儿免受传染病的侵害至关重要。检测严重急性呼吸综合征冠状病毒（SARS-CoV）-2感染患者的IgG水平可作为评估2019冠状病毒（COVID19）严重程度和预后的潜在策略。
外觀
冻干。缓冲液=0.01 M磷酸钠，0.25 M NaCl，pH值7.6和15 mg/ml BSA。不含防腐剂。
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
Sally Esmail et al.
Cell reports methods, 1(2), 100011-100011 (2021-07-09)
We have developed a rapid, accurate, and cost-effective serologic test for SARS-CoV-2 virus, which caused the COVID-19 pandemic, on the basis of antibody-dependent agglutination of antigen-coated latex particles. When validated using plasma samples that are positive or negative for SARS-CoV-2
PCSK9 prosegment chimera as novel inhibitors of LDLR degradation.
Saavedra, YG; Zhang, J; Seidah, NG
Testing null
Tara Bancroft et al.
Cellular immunology, 304-305, 35-43 (2016-05-24)
The recent increase in cases of whooping cough among teenagers in the US suggests that the acellular Bordetella pertussis vaccine (aP) that became standard in the mid 1990s might be relatively less effective than the whole-bacteria formulation (wP) previously used
Dorothee Winterberg et al.
Journal of clinical medicine, 10(12) (2021-07-03)
B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most frequent malignancy in children and also occurs in adulthood. Despite high cure rates, BCP-ALL chemotherapy can be highly toxic. This type of toxicity can most likely be reduced by antibody-based immunotherapy
Courtney Voss et al.
JCI insight, 6(13) (2021-06-04)
BACKGROUNDThe role of humoral immunity in COVID-19 is not fully understood, owing, in large part, to the complexity of antibodies produced in response to the SARS-CoV-2 infection. There is a pressing need for serology tests to assess patient-specific antibody response
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