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ABS463

Sigma-Aldrich

Anti-TET3 Antibody

from rabbit, purified by affinity chromatography

别名:

Ten-eleven-translocation family 3

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

human

技術

western blot: suitable

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... TET3(200424)

一般說明

Methylcytosine dioxygenase TET3 (TET3) is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. TET3 is involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization. TET3 is expressed in colon, muscle, adrenal gland, and peripheral blood lymphocytes. It is also expressed in fetal brain but not adult brain.

免疫原

KLH-conjugated linear peptide corresponding to human TET3.

應用

Anti-TET3 Antibody is a highly specific rabbit polyclonal antibody, that targets Methylcytosine dioxygenase TET3 & has been tested in western blotting.
Research Category
Signaling
Research Sub Category
Developmental Signaling

品質

Evaluated by Western Blotting/Peptide Inhibition Assay in SK-N-SH cell lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected TET3 in 15 µg of SK-N-SH cell lysate.

標靶描述

~200 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 3 isoforms at ~77 kDa, ~167 kDa, and ~180 kDa

外觀

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
SK-N-SH cell lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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A conceptual framework for understanding abnormal endometrial decidualization, with considerable significance for the diagnosis and treatment of abnormal decidualization-related changes in non-receptive endometrium in implantation failure during early pregnancy is very important. Here, we found the expression levels of miR-29a
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Leukemia, 36(4), 1150-1159 (2022-01-09)
Mitochondria can function as signaling organelles, and part of this output leads to epigenetic remodeling. The full extent of this far-reaching interplay remains undefined. Here, we show that MYC transcriptionally activates IDH2 and increases alpha-ketoglutarate (αKG) levels. This regulatory step
ZhiJun Qiu et al.
Cell chemical biology, 27(5), 538-550 (2020-02-27)
Mitochondrial D2HGDH and L2HGDH catalyze the oxidation of D-2-HG and L-2-HG, respectively, into αKG. This contributes to cellular homeostasis in part by modulating the activity of αKG-dependent dioxygenases. Signals that control the expression/activity of D2HGDH/L2HGDH are presumed to broadly influence

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