ABS232

Anti-MIXL1 Antibody

from rabbit, purified by affinity chromatography

• 别名: Homeobox protein MIXL1, Homeodomain protein MIX, hMix, MIX1 homeobox-like protein 1, Mix.1 homeobox-like protein
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 物種活性（以同源性預測）: primate (based on 100% sequence homology)
• 技術: immunocytochemistry: suitable; western blot: suitable
• NCBI登錄號: NP_114150
• UniProt登錄號: Q9H2W2
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... MIXL1(83881)

说明

一般說明

MIXL1 is also known as Homeobox protein MIXL1, Homeodomain protein MIX (hMix), MIX1 homeobox-like protein 1, and Mix.1 homeobox-like protein. MIXL1 is a transcription factor with roles in axial mesendoderm morphogenesis, endoderm formation, blood cell differentiation, and morphogenesis of the heart and the gut during embryogenesis. MIXL1 has been shown to negatively regulate brachyury expression. MIXL1 is expressed mainly in progenitors and secondary lymph tissues, immature B- and T-lymphoid cells during normal hematopoiesis, and is also present in differentiating embryonic stem cells.

特異性

Other homologies: Mouse and Rat (85% sequence homology).

This antibody recognizes the homeobox DNA binding domain of MIXL1.

免疫原

Epitope: Homeobox DNA binding domain

KLH-conjugated linear peptide corresponding to the homeobox DNA binding domain of human MIXL1.

應用

Anti-MIXL1 Antibody is a highly specific rabbit polyclonal antibody, that targets Homeobox protein MIXL1 & has been tested in western blotting & ICC.

Immunocytochemistry Analysis: A 1:200 dilution from a representative lot detected MIXL1 in H9 embryoid body cells. This protein was observed in H9 embryoid bodies (Lee, M. R., et al. (2010). Stem Cells. 28:1550-1559). MIXL1 was also localized in the nucleus of COS-7 and mouse ES cells (Mossman, A. K., et al. (2005). Stem Cells and Development. 14:656-663).

Research Category
Signaling

Research Sub Category
Developmental Signaling

品質

Evaluated by Western Blotting in Jurkat cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected MIXL1 in 10 µg of Jurkat cell lysate.

標靶描述

~36 kDa observed

外觀

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Jurkat cell lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable