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Merck
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Key Documents

AB5603A4

Sigma-Aldrich

Anti-Sox2, Alexa Fluor™ 488 Conjugate Antibody

from rabbit, ALEXA FLUOR™ 488

别名:

Transcription factor SOX-2

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

100

共軛

ALEXA FLUOR™ 488

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

human

物種活性（以同源性預測）

mouse (based on 100% sequence homology)

技術

immunocytochemistry: suitable

NCBI登錄號

NP_003097

UniProt登錄號

P48431

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... SOX2(6657)

一般說明

SOX2 is also known as SRY related HMG BOX gene 2. All SOX proteins have a single HMG box and bind linear DNA in a sequence-specific manner, resulting in the bending of DNA through large angles. Bending causes the DNA helix to open for some distance, which may affect binding and interactions of other transcription factors. SOX1, SOX2 and SOX3 show the closest homology to SRY. They share maximum homology within the HMG domain and are expressed mainly in the developing nervous system of the mouse. These genes share significant homology outside the HMG box also and are highly conserved throughout their evolution.

免疫原

Synthetic peptide from human Sox2.

應用

Detect Sox2 using this Anti-Sox2, Alexa Fluor 488 Conjugate Antibody validated for use in ICC.
Research Category
Neuroscience
Research Sub Category
Transcription Factors

品質

Evaluated by Immunocytochemistry in undifferentiated ReNcell VM neural progenitor cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Sox2 in undifferentiated ReNcell VM neural progenitor cells.

標靶描述

The unconjugated antibody (AB5603) tested on western blot detects Sox2 in whole cell or nuclear extracts as a protein band at 34 kDa

外觀

Affinity purified
Purified rabbit polyclonal conjugated to Alexa Fluor™ 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

儲存和穩定性

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

分析報告

Control
Undifferentiated ReNcell VM neural progenitor cells

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

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