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Merck
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主要文件

AB15562

Sigma-Aldrich

Anti-Transient Receptor Potential Channel 7 Antibody

Chemicon®, from rabbit

别名:

TRPM7, LTRPC7, Channel-kinase 1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

rat, mouse

製造商/商標名

Chemicon®

技術

immunocytochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

mouse ... Trpm7(58800)
rat ... Trpm7(679906)

特異性

Recognizes Transient Receptor Potential Channel 7 (TRPM7, LTRPC7, Channel-kinase 1).

免疫原

Purified peptide from the C-terminus of human TRPM7 (Accession number Q96QT4).

應用

Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
This Anti-Transient Receptor Potential Channel 7 Antibody is validated for use in IC, WB for the detection of Transient Receptor Potential Channel 7.
Western blot: 1:200-1:500 using ECL on mouse brain lysate and GH3 cell line (rat pituitary tumor) lysate.
Immunocytochemistry: 1:200 using GH3 cell line (rat pituitary tumor).
Dilutions should be made using a carrier protein such as BSA (1-3%).
Optimal working dilutions must be determined by the end user.

外觀

ImmunoAffinity Purified
Format: Purified
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.05% sodium azide as a preservative. Reconstitute with 200 uL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).

儲存和穩定性

Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

分析報告

Control
Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile deionized water. For negative control, preincubate 1 μg of peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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象形圖

Skull and crossbonesEnvironment

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Astrid Kollewe et al.
eLife, 10 (2021-11-13)
The transient receptor potential melastatin-subfamily member 7 (TRPM7) is a ubiquitously expressed membrane protein consisting of ion channel and protein kinase domains. TRPM7 plays a fundamental role in the cellular uptake of divalent cations such as Zn2+, Mg2+, and Ca2+

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