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Sigma-Aldrich

4-甲基伞形酮油酸酯

lipase substrate, ≥95% (HPCE), solid, suitable for fluorescence

别名:

油酸 4-甲基伞形酮酯

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About This Item

经验公式（希尔记法）:
C28H40O4
CAS号:
18323-58-5
分子量:
440.61
Beilstein:
4887028
EC號碼:
242-210-7
MDL號碼:
MFCD00076095
分類程式碼代碼:
12352204
PubChem物質ID:
57652555
NACRES:
NA.21

product name

4-甲基伞形酮油酸酯, suitable for fluorescence, ≥95% (HPCE)

化驗

≥95% (HPCE)

形狀

solid

儲存條件

protect from light
under inert gas

mp

37-38 °C (lit.)

溶解度

2-methoxyethanol: soluble
DMSO: soluble
chloroform: soluble

螢光

λex 312 nm in methanol
λex 327 nm; λem 449 nm in 0.1 M phosphate pH 7.0 (lipase)

適合性

suitable for fluorescence

運輸包裝

wet ice

儲存溫度

−20°C

SMILES 字串

CCCCCCCC\C=C/CCCCCCCC(=O)Oc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C28H40O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-27(29)31-24-19-20-25-23(2)21-28(30)32-26(25)22-24/h10-11,19-22H,3-9,12-18H2,1-2H3/b11-10-

InChI 密鑰

NKQFKJYKCVDLPT-KHPPLWFESA-N

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應用

4-甲基伞形油基油酸酯已被用于：
  • 作为测定非特异性酯酶活性的底物
  • 确定脂肪酶活性
  • 作为评估胰腺脂肪酶抑制活性的底物

包裝

无底玻璃瓶。内含物在插入的融合锥体内。

其他說明

脂肪酶的荧光底物

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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M L Armstrong et al.
The American journal of pathology, 125(2), 339-348 (1986-11-01)
The authors studied xanthomatous skin in cholesterol-fed rabbits for changes in lipid content and in activities of enzymes regulating intracellular lipid content. After 80 days of hypercholesterolemic diet, xanthomas were widespread and changes in lipid metabolism were marked. In both
Oleate lipase activity in Gardnerella vaginalis and reconsideration of existing biotype schemes
Moncla BJ and Pryke KM
BMC Microbiology, 9(1), 78-78 (2009)
Lysosomal acid lipase in cultivated fibroblasts: characterization of enzyme activity in normal and enzymatically deficient cell lines.
B K Burton et al.
Clinica chimica acta; international journal of clinical chemistry, 101(1), 25-32 (1980-02-14)
Fluorometric assay for the hydrolytic activity of lipase using fatty acyl esters of 4-methylumbelliferone.
T J Jacks et al.
Analytical biochemistry, 21(2), 279-285 (1967-11-01)
T J Van Berkel et al.
Biochimica et biophysica acta, 617(3), 446-457 (1980-03-21)
(1) Parenchymal and non-parenchymal cells were isolated from rat liver. The characteristics of acid lipase activity with 4-methylumbelliferyl oleate as substrate and acid cholesteryl esterase activity with cholesteryl[1-14C]oleate as substrate were investigated. The substrates were incorporated in egg yolk lecithin
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