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Merck
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文件

8.55116

Sigma-Aldrich

Methyl Indole AM resin

Novabiochem®

别名:

AM Methylindole Resin

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About This Item

分類程式碼代碼:
12352005
NACRES:
NA.22

品質等級

產品線

Novabiochem®

形狀

beads

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

製造商/商標名

Novabiochem®

應用

peptide synthesis

儲存溫度

2-8°C

一般說明

[3-((Methyl-Fmoc-amino)-methyl)indol-1-yl] acetyl AM resin is an extremely useful support for the production of N-methyl substituted carboxamides and sulfonamides, as well as peptide N-methylamides [1]. After first removing the Fmoc group, loading of the resin with Fmoc-amino acids can be effected using HATU/DIPEA. Cleavage with TFA directly provides the product N-methylamide.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins


Literature references

[1] K. G. Estep, et al. (1998) J. Org. Chem., 63, 5300.

聯結

Replaces: 01-64-0451

分析報告

Colour (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.60 - 1.00 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
The polymer matrix is copoly (styrene-1 % DVB), 100 - 200 mesh.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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商品

Novabiochem® has one of the most extensive ranges of linkers and derivatized resins for Fmoc solid phase peptide synthesis. These resins have varied properties with special protocols for loading and cleaving.

Novabiochem® has one of the most extensive ranges of linkers and derivatized resins for Fmoc solid phase peptide synthesis. These resins have varied properties with special protocols for loading and cleaving.

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