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Novabiochem®
形狀
beads
反應適用性
reaction type: Fmoc solid-phase peptide synthesis
製造商／商標名
Novabiochem®
應用
peptide synthesis
儲存溫度
2-30°C
一般說明
This support is useful for the production of peptide aldehydes and other carboxaldehydes. Following removal of the Fmoc group with 20% piperidine in DMF, acylation of the resin-bound methoxylamine is best effected using DIPCDI/HOAt or HATU/DIPEA activation. This results in formation of a supported Weinreb-type amide which can be either reduced to an aldehyde with LiAlH4 [1,2] or cleaved with Grignard reagents to give ketones [2,3].
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
聯結
Replaces: 01-64-0153
分析報告
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 1.00 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
The polymer matrix is copoly (styrene - 1 % DVB), 100 - 200 mesh
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 1.00 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
The polymer matrix is copoly (styrene - 1 % DVB), 100 - 200 mesh
法律資訊
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
商品
Novabiochem® has one of the most extensive ranges of linkers and derivatized resins for Fmoc solid phase peptide synthesis. These resins have varied properties with special protocols for loading and cleaving.
Novabiochem® has one of the most extensive ranges of linkers and derivatized resins for Fmoc solid phase peptide synthesis. These resins have varied properties with special protocols for loading and cleaving.
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