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Merck
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Key Documents

8.52246

Sigma-Aldrich

Fmoc-D-Tyr(PO(OBzl)OH)-OH

Novabiochem®

别名:

Fmoc-D-Tyr(PO(OBzl)OH)-OH, N-α-Fmoc-O-benzyl-D-phosphotyrosine

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About This Item

经验公式(希尔记法):
C31H28NO8P
分子量:
573.53
分類程式碼代碼:
12352209

品質等級

產品線

Novabiochem®

化驗

≥87.0% (acidimetric)
≥90.0% (HPLC)
≥95% (TLC)

形狀

powder

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

製造商/商標名

Novabiochem®

應用

peptide synthesis

官能基

Fmoc

儲存溫度

15-25°C

一般說明

An excellent building block for the preparation of D-phosphotyrosine-containing peptides by Fmoc SPPS. This derivative can be introduced using standard activation methods, such as PyBOP® and TBTU. The monoprotected phosphoserine residue once incorporated is stable to piperidine. Using this reagent, even peptides containing multiple phosphorylation sites can be prepared efficiently by standard Fmoc SPPS methods.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Fmoc SPPS of Peptides containing Post-Translational Modifications

聯結

Replaces: 04-13-1080

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): +14.0 - +18.0 °
Purity (TLC(CMA1)): ≥ 95 %
Assay (HPLC, area%): ≥ 90.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 87.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.3 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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