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品質等級
產品線
Novabiochem®
化驗
≥97.0% (HPLC)
≥98% (TLC)
形狀
powder
反應適用性
reaction type: Biotinylations
製造商/商標名
Novabiochem®
mp
163-165 °C
應用
peptide synthesis
儲存溫度
15-25°C
InChI
1S/C16H19N3O5S/c20-14(24-11-7-5-10(6-8-11)19(22)23)4-2-1-3-13-15-12(9-25-13)17-16(21)18-15/h5-8,12-13,15H,1-4,9H2,(H2,17,18,21)/t12-,13-,15-/m0/s1
InChI 密鑰
YUDNXDTXQPYKCA-YDHLFZDLSA-N
一般說明
Pre-activated reagent for the introduction of biotin by solid phase synthesis. More soluble and more reactive than 851023 [1]. This reagents has recently been found to be effective in SPOT synthesis of biotinylated peptides [2].
Associated Protocols and Technical Articles
Biotinylation Reagents for Peptide Synthesis
Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)
Literature references
[1] B. Baumeister, et al. Int. J. Pept. Res. Ther., 11, 139.
[2] D. Winkler & P. McGeer (2008) Proteomics, 8, 961.
Associated Protocols and Technical Articles
Biotinylation Reagents for Peptide Synthesis
Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)
Literature references
[1] B. Baumeister, et al. Int. J. Pept. Res. Ther., 11, 139.
[2] D. Winkler & P. McGeer (2008) Proteomics, 8, 961.
應用
- Mechanistic studies of a cell-permeant peptide designed to enhance myosin light chain phosphorylation: This study discusses the synthesis and applications of cell-permeant peptides involving biotin-ONP for enhanced cellular processes (Almansour, 2017).
- Structure-function analysis of tight junction-directed permeation enhancer PIP250: Provides insights into the utility of biotin-ONP in analyzing the structure and function of peptides used to enhance cellular permeation (Taverner et al., 2023).
聯結
Replaces: 01-63-0116
分析報告
Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in dioxan): +34.5 - +39.5 °
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in dioxan): +34.5 - +39.5 °
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
To see the solvent systems used for TLC of Novabiochem® products please click here.
法律資訊
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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